Last reviewed · How we verify
NCT03618979
A Trial Comparing Three Orthobiologic Therapies on Atrophied Multifidus Muscles in Patients With Low Back Pain
NA trial testing PPP treatment in Low Back Pain in 8 participants. Terminated before completion.
29 June 2022
Quick facts
| Lead sponsor | Regenexx, LLC |
|---|---|
| Phase | NA |
| Status | Terminated |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 8 |
| Start date | 2 May 2019 |
| Primary completion | 29 June 2022 |
| Estimated completion | 29 June 2022 |
| Sites | 2 locations across United States |
Drugs / interventions tested
- PPP treatment — full drug profile →
- PRP treatment — full drug profile →
- PRP and PL Combo treatment — full drug profile →
Conditions studied
- Low Back Pain — all drugs for Low Back Pain →
Sponsor
Regenexx, LLC — full company profile →
Who can join
Adults 18 to 75, any sex, with Low Back Pain. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
To evaluate and compare the effectiveness of 3 different injection treatments on multifidus atrophy and lower back pain.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Biomimetic Scaffolds in Skeletal Muscle Regeneration.
Mulbauer GD, Matthew HWT. · · 2019 · cited 28× · PMID 32309608 · DOI 10.15190/d.2019.3
Verify or expand the search:
- PubMed search for NCT03618979
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Low Back Pain
Currently open trials in the same condition.
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- NCT07535047 — Placebo-Induced Hypoalgesia During Transcutaneous Electrical Nerve Stimulation Application in Low Back Pain · NA · recruiting
- NCT07463729 — Evaluation of Stabilization Training With Biofeedback in Lumbosacral Spine Pain Syndrome · NA · recruiting
- NCT07250568 — Office Program Effects on Pain, Posture, Muscle Physiology, Stress, Ergonomics, and Quality of Life in LBP Workers · NA · recruiting
- NCT07467070 — Effectiveness of Pilates on Postural Correction, Core Strength and Flexibility in Younger Individuals With Non-specific · NA · recruiting
Other Regenexx, LLC trials
Trials by the same sponsor.
- NCT06924853 — Platelet Lysate vs Saline for Lumbosacral Radiculopathy · NA · terminated
- NCT05287867 — Trial for Treating Painful Degenerative Disc Disease · NA · recruiting
- NCT04661267 — Randomized Trial of Regenexx Stem Cell Support Formula · NA · completed
- NCT04487691 — Nebulized PL for Post-COVID-19 Syndrome · NA · terminated
- NCT03898388 — Correlating the OA Knee Microenvironment to Outcomes After Regenexx-SD Treatment: A Multi-Site Study · NA · terminated
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03618979 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Regenexx, LLC
- Last refreshed: 8 July 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03618979.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing