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NCT03618251: AVAAS

Automated Volume Assessment of Acute Stroke

Completed Last updated 17 September 2021
What this trial tests

trial testing specific MRI sequences in Stroke, Software Verification, Diffusion Weighted MRI, Neuroimaging in 406 participants. Completed in 4 December 2020.

Timeline
15 March 2018
Primary endpoint
4 September 2020
4 December 2020

Quick facts

Lead sponsorFondation Ophtalmologique Adolphe de Rothschild
StatusCompleted
Study typeOBSERVATIONAL
Enrollment406
Start date15 March 2018
Primary completion4 September 2020
Estimated completion4 December 2020
Sites1 location across France

Drugs / interventions tested

Conditions studied

Sponsor

Fondation Ophtalmologique Adolphe de Rothschild — full company profile →

Who can join

18 and older, any sex, with Stroke, Software Verification, Diffusion Weighted MRI, Neuroimaging. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Stroke is a common disease. It is increasingly managed in non-specialized centers. The volume of the lesion, evaluated on the diffusion weighted imaging, is a prognostic factor of clinical progression and is useful for the treatment decision. There is therefore a real interest in having a reliable software able to detect the stroke and evaluate the volume of the cerebral infarction. The aim is to provide rapid information to the interventional neuroradiologist and optimize the care of the patient. The Alberta Stroke Program Early Computed Tomography Score currently used to predict response to treatment divides the territory of the middle cerebral artery. It has a few limitations, it is unreproducible and concerns only the territory of the middle cerebral artery. Manual volumetry is a long and also not very reproducible technique. The aim of our study is to evaluate the reproducibility and diagnostic performances of the automated segmentation software based on the diffusion weighted imaging sequence, and to compare it to manual and semi-automatic measurements.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

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Data sources for this page

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