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NCT03616418: abilities

Ankle Brachial Index Combined With Serum Uric Acid Levels Improve Prediction All Cause Mortality and Cardiovascular Mortality in the Elderly Chinese Population

Completed Last updated 29 December 2021
What this trial tests

trial testing antiplatelet drugs;statins;antihypertensive drugs in Ankle Brachial Index in 3,026 participants. Completed in 1 August 2021.

Timeline
1 January 2017
Primary endpoint
1 August 2019
1 August 2021

Quick facts

Lead sponsorShanghai 10th People's Hospital
StatusCompleted
Study typeOBSERVATIONAL
Enrollment3,026
Start date1 January 2017
Primary completion1 August 2019
Estimated completion1 August 2021

Drugs / interventions tested

Conditions studied

Sponsor

Shanghai 10th People's Hospital

Who can join

65 and older, any sex, with Ankle Brachial Index. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Peripheral arterial disease (PAD) is a common clinical manifestation of the systemic atherosclerotic process, and the ankle brachial index (ABI) is an ideal tool to diagnose PAD. The association between high serum uric acid levels (SUA) and arterial stiffness as well as endothelial dysfunction has been demonstrated in humans and uric acid has been suggested to be an important modulator of the inflammatory process. It has also been confirmed by clinical studies. Currently, there have been few long term follow up studies focused on the whether serum uric acid levels combined with ankle brachial index can improve prediction all cause mortality and cardiovascular mortality,especially in China population.Therefore, the aim of this study was to elucidate whether ABIcombined with SUA can improve prediction all cause mortality and cardiovascular mortality in the elderly China population independently of the traditional Framingham Risk Score.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

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Other Shanghai 10th People's Hospital trials

Trials by the same sponsor.

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