NCT03616249: ESSE

Exercise and the Sleep for the Sarcopenic Elderly

Completed NA Last updated 2 March 2020

What this trial tests

NA trial testing Sleep in Sarcopenia in 28 participants. Completed in 10 December 2019.

Timeline

3 March 2017

Primary endpoint
10 October 2018

10 December 2019

Quick facts

Lead sponsor	Federal University of São Paulo
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	quadruple
Primary purpose	treatment
Enrollment	28
Start date	3 March 2017
Primary completion	10 October 2018
Estimated completion	10 December 2019
Sites	1 location across Brazil

Drugs / interventions tested

• Sleep
• Resistance Exercise

Conditions studied

• Sarcopenia — all drugs for Sarcopenia →
• Sleep — all drugs for Sleep →
• Physical Activity — all drugs for Physical Activity →

Sponsor

Federal University of São Paulo

Who can join

65 and older, any sex, with Sarcopenia or Sleep. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

International data indicate that approximately 10% of the elderly will be affected by sarcopenia, a multifactorial syndrome that leads to the progressive and generalized loss of mass and muscular strength, leading to a decrease in quality of life, increased physical dependence, fragility, morbidity And mortality. Parallel to aging, it is well described in the literature that older people present a phase advance, which promotes alteration in the sleep-wake rhythm, as well as reduction of sleep time and quality.

In this sense, two questions need to be answered: Do sarcosis elderly present major changes in sleep-wake rhythm and in sleep parameters when compared to non-sarcopenic elderly? The improvement of sarcopenia through resistance training is also related to the improvement of the sleep-wake rhythm of the sleep parameters. In order to answer these questions, the objective of the project is to evaluate whether sarcopenic individuals present changes in the sleep-wake rhythm and sleep quality at higher levels when compared to non-sarcopenic individuals and whether the benefits of resistance training for sarcopenic individuals are related to Regulation of sleep-wake rhythm and sleep patterns.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

1. Resistance Training Improves Sleep and Anti-Inflammatory Parameters in Sarcopenic Older Adults: A Randomized Controlled Trial.
   de Sá Souza H, de Melo CM, Piovezan RD, Miranda REEPC, et al · · 2022 · cited 29× · PMID 36498393 · DOI 10.3390/ijerph192316322