Last reviewed · How we verify
NCT03615365: CBRS2
COPD Breathing Record Study 2
trial in Chronic Obstructive Pulmonary Disease in 50 participants. Completed in 23 November 2018.
18 October 2018
Quick facts
| Lead sponsor | TidalSense |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 50 |
| Start date | 15 August 2017 |
| Primary completion | 18 October 2018 |
| Estimated completion | 23 November 2018 |
| Sites | 1 location across United Kingdom |
Conditions studied
- Chronic Obstructive Pulmonary Disease — all drugs for Chronic Obstructive Pulmonary Disease →
Sponsor
TidalSense
Who can join
40 and older, any sex, with Chronic Obstructive Pulmonary Disease. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The aim of this study is to collect capnometric (tidal breathing CO2) data using TidalSense's N-Tidal C Data Collector Device. The data collected will be examined for correlation with currently accepted assessment techniques for COPD (spirometry, vital signs and pulse oximetry) and the patient's clinical condition (stable, worsening, improving). The patient numbers and study duration have been determined by power calculations to provide a statistically significant sample size, based on expected number of exacerbations (mild, moderate and severe) from the patient cohort. The data will also be examined to assess the predictive possibility of a non-invasive self-care personal CO2 monitoring device to identify COPD exacerbations.
Publications & conference data
3 peer-reviewed publications reference this trial (live from Europe PMC):
-
Machine diagnosis of chronic obstructive pulmonary disease using a novel fast-response capnometer.
Talker L, Neville D, Wiffen L, Selim AB, et al · · 2023 · cited 2× · PMID 37268935 · DOI 10.1186/s12931-023-02460-z -
Quantification of smoking-related airway remodelling in COPD, using N-Tidal.
Lim RH, Talker L, Broomfield H, Dogan C, et al · · 2026 · PMID 41748706 · DOI 10.1038/s41598-026-41699-6 -
Diagnosis and Severity Assessment of COPD using a Novel Fast-Response Capnometer And Interpretable Machine Learning
Talker L, Dogan C, Neville D, Lim RH, et al · · 2023 · DOI 10.1101/2023.12.20.23300327
Verify or expand the search:
- PubMed search for NCT03615365
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Currently open trials in the same condition.
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- NCT07418736 — A Phase II Study of CM326 in Subjects With Moderate to Severe Chronic Obstructive Pulmonary Disease · Phase 2 · recruiting
- NCT07069829 — Study of Clinical and Patient-reported Outcomes in Adults With Moderate to Severe COPD Treated With Breztri/Trixeo · recruiting
Other TidalSense trials
Trials by the same sponsor.
- NCT04939558 — Cardiorespiratory Diagnostic Study · completed
- NCT04504838 — The Asthma Breathing Record Study · completed
- NCT03356288 — The General Breathing Record Study · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03615365 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by TidalSense
- Last refreshed: 2 June 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03615365.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing