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NCT03613857
Effect of Diabetes and Hepatic Enzymes Mutation on Clopidogrel VS Ticagrelor Activity in Myocardial Infarction (MI) Patients Undergoing Primary Percutaneous Coronary Intervention (PCI)
trial testing Clopidogrel in Myocardial Infarction in 1,022 participants. Completed in 28 July 2018.
28 July 2018
Quick facts
| Lead sponsor | Cairo University |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 1,022 |
| Start date | 15 April 2017 |
| Primary completion | 28 July 2018 |
| Estimated completion | 28 July 2018 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- Clopidogrel (clopidogrel) — full drug profile →
- Ticagrelor 90mg — full drug profile →
Conditions studied
- Myocardial Infarction — all drugs for Myocardial Infarction →
Sponsor
Cairo University
Who can join
Adults 20 to 80, any sex, with Myocardial Infarction. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
In this study the combined effect of diabetes mellitus and cyp2c19 polymorphism on platelet aggregation inhibitory activity of the highest traditionally used loading dose 600 mg clopidogrel and ticagrelor 180 mg loading dose will be compared in acute coronary syndrome (ACS) patients undergoing PCI.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Diabetes and CYP2C19 Polymorphism Synergistically Impair the Antiplatelet Activity of Clopidogrel Compared With Ticagrelor in Percutaneous Coronary Intervention-treated Acute Coronary Syndrome Patients.
Mohareb MW, AbdElghany M, Zaki HF, El-Abhar HS. · · 2020 · cited 12× · PMID 32675750 · DOI 10.1097/fjc.0000000000000881
Verify or expand the search:
- PubMed search for NCT03613857
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other recruiting trials for Myocardial Infarction
Currently open trials in the same condition.
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Other Cairo University trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03613857 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Cairo University
- Last refreshed: 14 January 2019
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03613857.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing