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NCT03610386: DA-TRPM8
Effects of an Anti-TRPM8 in the Atopic Dermatitis Pruritus
NA trial testing Adding menthoxypropanediol to the biopsy in Atopic Dermatitis in 10 participants. Completed in 29 January 2019.
29 January 2019
Quick facts
| Lead sponsor | University Hospital, Brest |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | non randomized |
| Design | parallel |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 10 |
| Start date | 21 November 2018 |
| Primary completion | 29 January 2019 |
| Estimated completion | 29 January 2019 |
| Sites | 1 location across France |
Drugs / interventions tested
- Adding menthoxypropanediol to the biopsy
- No adding menthoxypropanediol to the biopsy
Conditions studied
- Atopic Dermatitis — all drugs for Atopic Dermatitis →
Sponsor
University Hospital, Brest
Who can join
18 and older, any sex, with Atopic Dermatitis. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The aim of the study is to analyse the effect of the menthoxypropanediol, a derivative of menthol, on the pruritus of atopic dermatitis (ex vivo study).
Publications & conference data
4 peer-reviewed publications reference this trial (live from Europe PMC):
-
TRP (transient receptor potential) ion channel family: structures, biological functions and therapeutic interventions for diseases.
Zhang M, Ma Y, Ye X, Zhang N, et al · · 2023 · cited 303× · PMID 37402746 · DOI 10.1038/s41392-023-01464-x -
TRPM8 Channels: Advances in Structural Studies and Pharmacological Modulation.
Izquierdo C, Martín-Martínez M, Gómez-Monterrey I, González-Muñiz R. · · 2021 · cited 54× · PMID 34445208 · DOI 10.3390/ijms22168502 -
New and Upcoming Topical Treatments for Atopic Dermatitis: A Review of the Literature.
Sideris N, Paschou E, Bakirtzi K, Kiritsi D, et al · · 2022 · cited 28× · PMID 36078904 · DOI 10.3390/jcm11174974 -
Physiological functions and pharmacological targeting of transient receptor potential channels.
Chubanov V, Grimm C, Hill K, Schaefer M, et al · · 2025 · PMID 41118703 · DOI 10.1016/j.pharmr.2025.100089
Verify or expand the search:
- PubMed search for NCT03610386
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Atopic Dermatitis
Currently open trials in the same condition.
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- NCT07488065 — A Study of SKB575 (HBM7575) Injection in Healthy Participants and Atopic Dermatitis Participants · Phase 1 · recruiting
- NCT07467564 — The Impact of Dupilumab Treatment on Anxiety and Depression Symptoms in Patients With Moderate-to-Severe Atopic Dermatit · recruiting
- NCT07358156 — A Study to Compare the Pharmacokinetics, Pharmacodynamic, Immunogenicity, and Safety of CKD-706 With US-Dupixent®, and E · Phase 1 · recruiting
Other University Hospital, Brest trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03610386 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University Hospital, Brest
- Last refreshed: 28 December 2021
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03610386.
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