Last reviewed · How we verify
NCT03609866
Chest Physiotherapy Effects on Intracranial Pressure
NA trial testing rapid thoracic compression technique in Acute Brain Injury in 50 participants. Completed in 30 December 2023.
30 September 2023
Quick facts
| Lead sponsor | University of Santiago de Compostela |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | basic science |
| Enrollment | 50 |
| Start date | 1 April 2021 |
| Primary completion | 30 September 2023 |
| Estimated completion | 30 December 2023 |
| Sites | 1 location across Spain |
Drugs / interventions tested
- rapid thoracic compression technique
- inferior limb passive mobilization
Conditions studied
- Acute Brain Injury — all drugs for Acute Brain Injury →
Sponsor
University of Santiago de Compostela
Who can join
18 and older, any sex, with Acute Brain Injury. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The investigators will study the effects of a chest physiotherapy technique (rapid thoracic compression) on the intracranial pressure of individuals with acute cerebral injury and with need of intubated mechanical ventilation
Publications & conference data
3 peer-reviewed publications reference this trial (live from Europe PMC):
-
Rapid chest compression effects on intracranial pressure in patients with acute cerebral injury.
Rodrigues-Gomes RM, Martí JD, Rolán RM, Gelabert-González M. · · 2022 · cited 6× · PMID 35428364 · DOI 10.1186/s13063-022-06189-w -
Effects of rapid chest compression technique on intracranial and cerebral perfusion pressures in acute neurocritical patients: a randomized controlled trial.
Rodrigues-Gomes RM, Prieto Campo Á, Martinez Rolán R, Gelabert-González M. · · 2025 · cited 1× · PMID 40270039 · DOI 10.1186/s13054-025-05405-8 -
Expiratory Flow Bias and Physiological Effects of Rapid Chest Compression in Mechanically Ventilated Neurocritical Patients: A Secondary Analysis of a Randomized Controlled Trial.
Rodrigues-Gomes RM, Martinez Rolán R, Botana-Rial M, Del Río González A, et al · · 2025 · PMID 41010720 · DOI 10.3390/jcm14186516
Verify or expand the search:
- PubMed search for NCT03609866
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other recruiting trials for Acute Brain Injury
Currently open trials in the same condition.
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- NCT06426615 — Connectivity and Neural Signatures of Consciousness in Unresponsive States · NA · recruiting
- NCT04080440 — Brain-injured Patients Extubation Readiness Study · NA · recruiting
Other University of Santiago de Compostela trials
Trials by the same sponsor.
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- NCT07430748 — REGENFAST vs L-PRF in Periodontal Regeneration · EARLY_PHASE1 · active not recruiting
- NCT07355673 — The Influence of Isolation Techniques in Gingival Irritation During an In-office Bleaching · NA · completed
- NCT07355647 — Efficacy of a Desensitizing Agent During In-Office Bleaching · EARLY_PHASE1 · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03609866 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Santiago de Compostela
- Last refreshed: 24 April 2024
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03609866.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing