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NCT03609749
Mindful Self-Regulation fMRI Study (MindfulPCfMRI)
NA trial testing Mindfulness Training for Primary Care in Anxiety in 21 participants. Terminated before completion.
1 April 2020
Quick facts
| Lead sponsor | Cambridge Health Alliance |
|---|---|
| Phase | NA |
| Status | Terminated |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | basic science |
| Enrollment | 21 |
| Start date | 30 January 2019 |
| Primary completion | 1 April 2020 |
| Estimated completion | 1 August 2020 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Mindfulness Training for Primary Care
Conditions studied
- Anxiety — all drugs for Anxiety →
- Depression — all drugs for Depression →
Sponsor
Cambridge Health Alliance — full company profile →
Who can join
Adults 21 to 60, any sex, with Anxiety or Depression. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The purpose of this study is to investigate changes in functional neural activation during self-regulation tasks before compared to after the Mindfulness Training for Primary Care intervention (see MINDFUL-PC (Phase 3) clinical trial). The study will also look at whether chronic disease self-management action plan initiation and successful engagement of self-report and behavioral self-regulation targets relates to the observed brain activation changes after compared to before the mindfulness intervention.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Neural regulation of pain anticipation is associated with mindful behavior change in patients with anxiety or depression: A pilot study.
Datko M, Lutz J, Gawande R, Comeau A, et al · · 2025 · cited 1× · PMID 39752812 · DOI 10.1016/j.pscychresns.2024.111941
Verify or expand the search:
- PubMed search for NCT03609749
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Mindfulness Training for Primary Care
Trials testing the same drug.
- NCT04268355 — MINDFUL-PC for Portuguese Speakers Pilot Study 2020 · NA · terminated
- NCT03609450 — Integrating Mindfulness Into the Patient-Centered Medical Home (Phase 3) · NA · terminated
- NCT03265600 — Integrating Mindfulness Into the Patient-Centered Medical Home (Phase 2) · NA · completed
Other recruiting trials for Anxiety
Currently open trials in the same condition.
- NCT07336238 — Group Retreat Psilocybin Therapy for the Treatment of Anxiety and Depression in Patients With Metastatic Solid Tumors or · Phase 2 · recruiting
- NCT07522944 — AI-Guided Relaxation for Hemodialysis Anxiety · NA · recruiting
- NCT07466875 — Auricular Stimulation for Nicotine Withdrawal in Psychiatric Inpatients · NA · recruiting
- NCT07425951 — Building Cognitive Behavioural Skills With StoryBooks to Reduce Emotional Difficulties in Kindergarten Years · NA · recruiting
- NCT07473505 — Integrative Bilateral Cervical Sympathetic Blocks for Trauma-Related Symptoms in Special Operations Veterans: A Prospect · recruiting
Other Cambridge Health Alliance trials
Trials by the same sponsor.
- NCT06419595 — Screening and Support for Youth (SASY) · NA · not yet recruiting
- NCT07513220 — The Effectiveness and Acceptability of Formal Versus Informal Mindful Self-Compassion for Adolescents · NA · not yet recruiting
- NCT06988462 — Pilot Study of "Bottarga" Supplementation: A Little-known, Sustainable "Blue" Food · NA · recruiting
- NCT06564948 — Treatment for Individuals Interacting with the Criminal Justice System · NA · recruiting
- NCT06765122 — Program for Alleviating and Reducing Trauma and Stress for Intimate Partner Violence · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03609749 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Cambridge Health Alliance
- Last refreshed: 13 November 2020
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03609749.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing