NCT03603691 is a NA clinical trial of Modified Manual Muscle Test in Multiple Sclerosis, sponsored by Nanco van der Maas.

Who is sponsoring NCT03603691?

NCT03603691 is sponsored by Nanco van der Maas.

What drugs are being tested in NCT03603691?

Interventions in NCT03603691: Modified Manual Muscle Test, BMRC manual muscle test, MicroFET2 handhold dynamometer, Modified Tardieu Scale, Fatigue Scale for Motor and Cognitive Functions, numeric rating scale Fatigue.

What condition does NCT03603691 study?

NCT03603691 studies Multiple Sclerosis.

Is NCT03603691 still recruiting?

NCT03603691 is currently completed. Last updated 30 January 2019.

Last reviewed 2019-01-30 · How we verify

NCT03603691

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Study to Evaluate the Reliability and Validity of the Modified Manual Muscle Test for Persons With MS

Completed NA Last updated 30 January 2019

What this trial tests

NA trial testing Modified Manual Muscle Test in Multiple Sclerosis in 28 participants. Completed in 29 January 2019.

Timeline

1 August 2018

Primary endpoint
15 December 2018

29 January 2019

Quick facts

Lead sponsor	Nanco van der Maas
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	crossover
Masking	single
Primary purpose	diagnostic
Enrollment	28
Start date	1 August 2018
Primary completion	15 December 2018
Estimated completion	29 January 2019
Sites	1 location across Switzerland

Drugs / interventions tested

Modified Manual Muscle Test
BMRC manual muscle test
MicroFET2 handhold dynamometer
Modified Tardieu Scale
Fatigue Scale for Motor and Cognitive Functions
numeric rating scale Fatigue

Conditions studied

Multiple Sclerosis — all drugs for Multiple Sclerosis →

Sponsor

Nanco van der Maas

Who can join

18 and older, any sex, with Multiple Sclerosis. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Many patients with multiple sclerosis (MS) are treated with physiotherapy. Muscle weakness is a common symptom. It can be evaluated with a variety of muscle function tests. In MS patients, testing muscle function can be confounded by many factors, such as spasticity and ataxia, which are not considered by the existing tests and may cause biased test results. Steinlin Egli described a Modified Manual Muscle Test (MMMT) that considers spasticity and may provide a more reliable and valid muscle function test for MS patients. The investigators aim to evaluate the inter- and intra-rater reliability of the Modified Manual Muscle Test in MS and evaluate the validity of the Modified MMT according to the criteria of the 6 level British Medical Research Council (BMRC) manual muscle test and the microFET2 handhold dynamometer.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

The reliability of the modified Manual Muscle Test for persons with MS
Maas NAVd, Egli RS, Vogt DR, D’Souza M. · · 2025 · DOI 10.21203/rs.3.rs-7576603/v1

Verify or expand the search:

Other recruiting trials for Multiple Sclerosis

Currently open trials in the same condition.

NCT07507084 — The Effect of Internal- or External-Focused Exercise Training, Administered in Conjunction With a Cognitive Task, on Wal · NA · recruiting
NCT07524231 — Evaluation of the Effects of Laughter Yoga · NA · recruiting
NCT07489794 — URINARY INCONTINENCE AND PELVIC FLOOR MUSCLE ACTIVITY IN MULTIPLE SCLEROSIS · recruiting
NCT07236684 — Identification of Factors Related to UI in Patients With MS and EMG Assessment of PFM Activity · recruiting
NCT07500727 — Skeletal Muscle Aging and Responsiveness in Aged People With MS · NA · recruiting

Other Nanco van der Maas trials

Trials by the same sponsor.

NCT03871920 — Psychometric Evaluation of the Short Patient Evaluation Questionnaire · unknown

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03603691 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Nanco van der Maas
Last refreshed: 30 January 2019

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03603691.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing