NCT03599687: SATIATED

Soiled Airway Tracheal Intubation and the Effectiveness of Decontamination by Paramedics

Completed Results posted Last updated 13 August 2020

What this trial tests

trial testing Training in SALAD technique in Airway Management in 164 participants. Completed in 28 February 2019.

Timeline

16 July 2018

Primary endpoint
3 December 2018

28 February 2019

Quick facts

Lead sponsor	Yorkshire Ambulance Service NHS Trust
Status	Completed
Study type	OBSERVATIONAL
Enrollment	164
Start date	16 July 2018
Primary completion	3 December 2018
Estimated completion	28 February 2019
Sites	1 location across United Kingdom

Drugs / interventions tested

• Training in SALAD technique

Conditions studied

• Airway Management — all drugs for Airway Management →
• Intubation, Intratracheal — all drugs for Intubation, Intratracheal →
• Laryngoscopy — all drugs for Laryngoscopy →
• Vomiting — all drugs for Vomiting →

Sponsor

Yorkshire Ambulance Service NHS Trust

Who can join

Adults 18 to 65, any sex, with Airway Management or Intubation, Intratracheal. Patients with the condition only — healthy volunteers not accepted.

Results — posted to ClinicalTrials.gov

Per-arm endpoint measurements with 95% confidence intervals where reported. Source: trial results section.

Difference in First-pass Intubation Success Rates Before and After SALAD Training Primary · pre- and post-training as part of 2 hour study session

This measure is a comparison of Group AAB's first-pass intubation success rate, using an attempt which occurred before SALAD training, and Group ABB's intubation success rate, using an intubation attempt that occurred after SALAD training.

Group	Value	95% CI
Group AAB	44
Group ABB	74

Difference Between Mean Time Taken (in Seconds) to Perform a Successful Intubation on the First- Attempt, Before and After SALAD Training Approximately 30 Minutes Apart. Secondary · seconds

Group	Value	95% CI
Group AAB	15.4	± 3.5
Group ABB	3.7	± 3.4

Difference in Success Rates Between Participants Who Have Two Post-training Intubation Attempts Versus Participants Who Only Have One Post-training Intubation Attempt Secondary · pre- and post-training as part of 2 hour study session

Group	Value	95% CI
Group AAB	71
Group ABB	73

Sponsor's own description

In more than one-in-five cases of out-of-hospital cardiac arrest, airways are blocked by vomit and blood. Sometimes, paramedics cannot clear the airway using methods they have been taught. If the airway cannot be cleared, the patient will die.

Usually, these patients will have a breathing tube placed into their windpipe (intubation), as this provides protection from vomit and blood. To do this, the paramedic needs to be able to see the entrance to the windpipe.

A new method of clearing the airway called SALAD has been used in patients to help insert a breathing tube, but it is not known whether the method can help paramedics. This study will use a manikin to see if paramedics can insert a breathing tube more often on their first attempt, using SALAD.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

1. Soiled airway tracheal intubation and the effectiveness of decontamination by paramedics (SATIATED): a randomised controlled manikin study.
   Pilbery R, Teare MD. · · 2019 · cited 5× · PMID 33328824 · DOI 10.29045/14784726.2019.06.4.1.14
2. Soiled airway tracheal intubation and the effectiveness of decontamination by paramedics: a randomised controlled manikin study protocol.
   Pilbery R, Teare MD, Millins M. · · 2018 · cited 2× · PMID 33328808 · DOI 10.29045/14784726.2018.12.3.3.16