Who is sponsoring NCT03599336?

NCT03599336 is sponsored by Mayo Clinic.

What drugs are being tested in NCT03599336?

Interventions in NCT03599336: Reverse Total Shoulder Arthroplasty (rTSA), Nonoperative Treatment.

What condition does NCT03599336 study?

NCT03599336 studies Humerus Fracture, Humerus, Shoulder Fractures, Shoulder Arthropathy Associated With Other Conditions, Arthropathy Shoulder, Shoulder Injury, Arthropathy.

Is NCT03599336 still recruiting?

NCT03599336 is currently terminated. Last updated 11 October 2021.

Last reviewed 2021-10-11 · How we verify

NCT03599336

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

RSA vs. Nonop for 3 & 4-Part Proximal Humerus Fractures

Terminated NA Last updated 11 October 2021

What this trial tests

NA trial testing Reverse Total Shoulder Arthroplasty (rTSA) in Humerus Fracture in 4 participants. Terminated before completion.

Timeline

1 August 2018

Primary endpoint
29 October 2020

29 October 2020

Quick facts

Lead sponsor	Mayo Clinic
Phase	NA
Status	Terminated
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	treatment
Enrollment	4
Start date	1 August 2018
Primary completion	29 October 2020
Estimated completion	29 October 2020
Sites	1 location across United States

Drugs / interventions tested

Reverse Total Shoulder Arthroplasty (rTSA)
Nonoperative Treatment

Conditions studied

Humerus Fracture — all drugs for Humerus Fracture →
Humerus — all drugs for Humerus →
Shoulder Fractures — all drugs for Shoulder Fractures →
Shoulder Arthropathy Associated With Other Conditions — all drugs for Shoulder Arthropathy Associated With Other Conditions →

Sponsor

Mayo Clinic

Who can join

65 and older, any sex, with Humerus Fracture or Humerus. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

There is currently no consensus amongst orthopedic specialists on the best way to treat 3- and 4-part proximal humerus fractures. No surgery and surgery with a type of shoulder replacement called a reverse total shoulder arthroplasty are two options that many orthopedists use. This study is being performed to evaluate the differences in short- and long-term pain and functional outcomes between patients who are treated with these two different options.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Interventions for treating proximal humeral fractures in adults.
Handoll HH, Elliott J, Thillemann TM, Aluko P, et al · · 2022 · cited 79× · PMID 35727196 · DOI 10.1002/14651858.cd000434.pub5
Assessment of therapeutic clinical trials for proximal humeral fractures.
Koa J, Fares MY, Daher M, Abboud JA. · · 2024 · cited 2× · PMID 38556914 · DOI 10.5397/cise.2023.00521

Verify or expand the search:

Other recruiting trials for Humerus Fracture

Currently open trials in the same condition.

NCT06869343 — Early Versus Delayed Rehabilitation After Reverse Total Shoulder Arthroplasty for Proximal Humerus Fracture · NA · recruiting
NCT06113614 — Effects of Photobiomodulation on Functional Recovery of Proximal Humerus Fractures · NA · recruiting
NCT05668182 — A Case Series: TRUMATCH Graft Cage for Segmental Long Bone Defects · recruiting

Other Mayo Clinic trials

Trials by the same sponsor.

NCT07126548 — A Point of Prostate Cancer Diagnosis Virtual Reality Assistant Intervention in Supporting Newly Diagnosed Black Men · NA · not yet recruiting
NCT07221656 — Evaluation of Prolonged Asparaginase Activity Levels After Calaspargase Pegol Administration · not yet recruiting
NCT06891001 — The Utilization of a Shoe Insert on Individuals With Unilateral Greater Trochanteric Pain Syndrome on Single Leg Stance, · NA · not yet recruiting
NCT07169799 — Impact of Cryotherapy Spray (Tru-Freeze) for the Eradication of Gastric Antral Vascular Ectasia (ICE-GAVE) · NA · recruiting
NCT07086183 — Perioperative Risk in Patients on Chronic Aspirin Undergoing Craniotomy · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03599336 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Mayo Clinic
Last refreshed: 11 October 2021

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03599336.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing