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NCT03597542
Examining the Relationship Between Acute Meal Intake and Inflammation in Children
NA trial testing Eggs and Carbohydrates in Obesity in 36 participants. Completed in 2 February 2018.
2 February 2018
Quick facts
| Lead sponsor | University of Illinois at Urbana-Champaign |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | crossover |
| Masking | double |
| Primary purpose | basic science |
| Enrollment | 36 |
| Start date | 29 August 2017 |
| Primary completion | 2 February 2018 |
| Estimated completion | 2 February 2018 |
| Sites | 1 location across United States |
Drugs / interventions tested
- Eggs and Carbohydrates
Conditions studied
- Obesity — all drugs for Obesity →
- Inflammation — all drugs for Inflammation →
Sponsor
University of Illinois at Urbana-Champaign
Who can join
Adults 7 to 17, any sex, with Obesity or Inflammation. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Recent evidence has shown that obese and overweight children exhibit states of chronic inflammation. In obese adults, a high carbohydrate meal induces an inflammatory response; however, the effects of a high carbohydrate meal on biomarkers of inflammation has not previously been examined in children. The purpose of this research project is to characterize the inflammatory response to a high carbohydrate versus a low carbohydrate meal in healthy weight, overweight, and obese children (age 7-17 years). After completing informed consent/assent, a Dual-energy X-ray Absorptiometry (DXA) scan, and baseline blood draw on experimental day 1, children will then return to the lab two times to ingest either a high or low carbohydrate beverage followed by post-meal blood collection for a total of 3 blood draws. Biomarkers of inflammation will be analyzed by flow cytometry and enzyme-linked immunosorbent assay (ELISA). Participants will be recruited through various studies through the Neurocognitive Kinesiology Lab/Body Composition and Nutritional Neuroscience Labs as well as through the local Champaign-Urbana community. Data from this project will provide a better understanding of the inflammatory response to different meals in healthy weight, overweight, and obese children.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
A Carbohydrate Beverage Reduces Monocytes Expressing TLR4 in Children with Overweight or Obesity.
Niemiro GM, Chiarlitti NA, Khan NA, De Lisio M. · · 2020 · cited 3× · PMID 31825075 · DOI 10.1093/jn/nxz294
Verify or expand the search:
- PubMed search for NCT03597542
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03597542 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University of Illinois at Urbana-Champaign
- Last refreshed: 31 July 2018
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03597542.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing