NCT03596879 (PPD) is a NA clinical trial of dCBTI in Insomnia, sponsored by Henry Ford Health System.

Who is sponsoring NCT03596879?

NCT03596879 is sponsored by Henry Ford Health System.

What drugs are being tested in NCT03596879?

Interventions in NCT03596879: dCBTI, Sleep Education.

What condition does NCT03596879 study?

NCT03596879 studies Insomnia, Post Partum Depression.

Is NCT03596879 still recruiting?

NCT03596879 is currently completed. Last updated 5 December 2019.

Last reviewed 2019-12-05 · How we verify

NCT03596879: PPD

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Insomnia and Rumination in Late Pregnancy and the Risk for Postpartum Depression

Completed NA Last updated 5 December 2019

What this trial tests

NA trial testing dCBTI in Insomnia in 91 participants. Completed in 31 July 2019.

Timeline

18 July 2018

Primary endpoint
31 July 2019

31 July 2019

Quick facts

Lead sponsor	Henry Ford Health System
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	none
Primary purpose	treatment
Enrollment	91
Start date	18 July 2018
Primary completion	31 July 2019
Estimated completion	31 July 2019
Sites	1 location across United States

Drugs / interventions tested

dCBTI
Sleep Education

Conditions studied

Insomnia — all drugs for Insomnia →
Post Partum Depression — all drugs for Post Partum Depression →

Sponsor

Henry Ford Health System — full company profile →

Who can join

18 and older, female only, with Insomnia or Post Partum Depression. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The primary objective of the proposed research is to determine whether prenatal insomnia and ruminative thinking predict severity of postpartum depression (PPD) symptoms. Additionally, the investigators will also determine the effectiveness of digital/internet-based Cognitive Behavioral Therapy for Insomnia (dCBTI) in reducing the risk for PPD.

Publications & conference data

5 peer-reviewed publications reference this trial (live from Europe PMC):

A randomized controlled trial of digital cognitive behavioral therapy for insomnia in pregnant women.
Kalmbach DA, Cheng P, O'Brien LM, Swanson LM, et al · · 2020 · cited 93× · PMID 32559716 · DOI 10.1016/j.sleep.2020.03.016
Depression and suicidal ideation in pregnancy: exploring relationships with insomnia, short sleep, and nocturnal rumination.
Kalmbach DA, Cheng P, Ong JC, Ciesla JA, et al · · 2020 · cited 68× · PMID 31710876 · DOI 10.1016/j.sleep.2019.07.010
Mindfulness and nocturnal rumination are independently associated with symptoms of insomnia and depression during pregnancy.
Kalmbach DA, Roth T, Cheng P, Ong JC, et al · · 2020 · cited 35× · PMID 32146168 · DOI 10.1016/j.sleh.2019.11.011
Examining Patient Feedback and the Role of Cognitive Arousal in Treatment Non-response to Digital Cognitive-behavioral Therapy for Insomnia during Pregnancy.
Kalmbach DA, Cheng P, Roth T, Swanson LM, et al · · 2022 · cited 25× · PMID 33719795 · DOI 10.1080/15402002.2021.1895793
Racial disparities in treatment engagement and outcomes in digital cognitive behavioral therapy for insomnia among pregnant women.
Kalmbach DA, Cheng P, Reffi AN, Seymour GM, et al · · 2023 · cited 24× · PMID 36456448 · DOI 10.1016/j.sleh.2022.10.010

Verify or expand the search:

Other trials of dCBTI

Trials testing the same drug.

NCT02988375 — Sleep to Prevent Evolving Affecting Disorders · NA · completed

Other recruiting trials for Insomnia

Currently open trials in the same condition.

NCT07384429 — Effects of Lemborexant on Motor-sleep Comorbidity in Parkinson's Disease · Phase 4 · recruiting
NCT07270406 — Healthy Behaviors for Insomnia Prevention in People With HIV and Ongoing Pain · NA · recruiting
NCT07071324 — CF Wellness Program · NA · recruiting
NCT07417813 — A Multicenter Observational Study of Lemborexant on Insomnia Patients With Psychiatric Disorders · recruiting
NCT06348082 — Project Women's Insomnia Sleep Health Equity Study (WISHES) · NA · recruiting

Other Henry Ford Health System trials

Trials by the same sponsor.

NCT07450183 — Perioperative Cemiplimab for Resectable Non-Small Cell Lung Cancer With High PD-L1 · Phase 2 · not yet recruiting
NCT07418853 — Comparison of Goniotomy Device Outcomes in Combined Phacoemulsification-goniotomy Surgeries · NA · not yet recruiting
NCT06670287 — The Use of Multiple Sensors to Track Sleep in Nightshift Workers · NA · recruiting
NCT07363525 — Michigan Initial Experience Using Tigertriever for Thrombectomy · not yet recruiting
NCT07530172 — Radioembolization Versus External Radiation Therapy · Phase 2 · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03596879 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Henry Ford Health System
Last refreshed: 5 December 2019

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03596879.

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