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Dose-response Effect of Dietary Nitrate on Muscle Function in Older Individuals

NCT03595774 PHASE1 COMPLETED Results posted

Nitrate is a naturally-occurring substance found in foods, especially green leafy vegetables and beets. Increasing nitrate intake (by drinking beetroot juice (BRJ) has been shown to improve muscle function young and middle-aged subjects, athletes, and patients with heart failure. The purpose of this study is to determine whether dietary nitrate provides a similar benefit in older individuals, and if so, the optimal dose. We will be comparing the effects of ingesting BRJ containing a smaller or greater amount of nitrate versus the effects of a placebo (BRJ from which the nitrate has been removed).

Details

Lead sponsorIndiana University
PhasePHASE1
StatusCOMPLETED
Enrolment13
Start dateSat Sep 01 2018 00:00:00 GMT+0000 (Coordinated Universal Time)
CompletionSat Jul 31 2021 00:00:00 GMT+0000 (Coordinated Universal Time)

Conditions

Interventions

Countries

United States