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NCT03590730: BEAT
Benefits of ICD for the Primary Prevention in Patients With Valvular Cardiomyopathy
trial testing ICD implantation in Valvular Heart Disease in 12 participants. Terminated before completion.
10 July 2019
Quick facts
| Lead sponsor | Keimyung University Dongsan Medical Center |
|---|---|
| Status | Terminated |
| Study type | OBSERVATIONAL |
| Enrollment | 12 |
| Start date | 15 November 2017 |
| Primary completion | 10 July 2019 |
| Estimated completion | 15 July 2021 |
| Sites | 12 locations across South Korea |
Drugs / interventions tested
- ICD implantation
Conditions studied
- Valvular Heart Disease — all drugs for Valvular Heart Disease →
- Implantable Cardioverter Defibrillator — all drugs for Implantable Cardioverter Defibrillator →
- Sudden Cardiac Death — all drugs for Sudden Cardiac Death →
- Primary Prevention — all drugs for Primary Prevention →
Sponsor
Keimyung University Dongsan Medical Center
Who can join
Adults 19 to 75, any sex, with Valvular Heart Disease or Implantable Cardioverter Defibrillator. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The prevalence of valvular heart disease is on the rise along with the aging society and the generalization of echocardiography. Furthermore, the rheumatic valvular heart disease is much more prevalent in Asia than in Western countries, and the frequency of valve disease is higher in Asia. The effect of an implantable cardioverter defibrillator (ICD) in the primary prevention of sudden cardiac death in ischemic cardiomyopathy is well established and has become a standard of care. However, there is limited research on the effect of ICD implantation for primary prevention in patients with heart failure due to valvular heart disease. In a small study, the incidence of fatal cardiac arrhythmia was lower in patients with valvular cardiomyopathy (5%) who received ICD implantation for primary prevention than in those with ischemic cardiomyopathy. But there is also a report that the appropriate ICD treatment is not different from that of ischemic heart disease in valvular heart disease patients. Therefore, it is necessary to study the primary prevention effect of ICD on valvular cardiomyopathy in a larger number of patients. The purpose of this study was to investigate the effect of ICD on the prevention of sudden cardiac death in patients with heart failure due to valvular heart disease through prospective, multicenter, and observational studies.
Publications & conference data
No peer-reviewed publications indexed yet for this trial.
Verify or expand the search:
- PubMed search for NCT03590730
- Europe PMC full search
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Related trials
Other trials of ICD implantation
Trials testing the same drug.
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- NCT05373940 — Cardioverter DefIbriIlator PlacEMent for priMary Prevention of Sudden cArdiac Death in Patients Older Than 70 Years · NA · recruiting
- NCT05539898 — Improving the Criteria for Selecting Patients for Primary Prevention of Sudden Cardiac Death by Arrhythmic Risk Stratifi · NA · unknown
- NCT01722942 — Amiodarone Against ICD Therapy in Chagas Cardiomyopathy for Primary Prevention of Death · NA · unknown
Other recruiting trials for Valvular Heart Disease
Currently open trials in the same condition.
- NCT07197736 — DELINEATE-Prospective · recruiting
- NCT07042529 — Optimized Expansion of the Implanted Transcatheter Aortic Valve · NA · recruiting
- NCT07065500 — Mechanism and Effect of Novel Metabolites on Valvular Heart Disease · recruiting
- NCT07099417 — Screening of Valvular Heart Disease Using Single-channel Electrocardiogram · recruiting
- NCT06386016 — Detection of Valvular Heart Disease Using Artificial Intelligence-based Stethoscope · recruiting
Other Keimyung University Dongsan Medical Center trials
Trials by the same sponsor.
- NCT06963424 — Pain Relief and and Peripheral Perfusion Index During Erector Spinae Block · NA · completed
- NCT06471907 — Comparison of Pain Relief and Peripheral Perfusion Index · NA · recruiting
- NCT07210073 — Video Education to Improve Blood Pressure Control in Patients With Ischemic Heart Disease and Hypertension (V-EDUCATE) · NA · completed
- NCT06149299 — Great Occipital Nerve Block Using Different Approach · NA · unknown
- NCT05705362 — Simple Crossover Versus Side Branch Opening in Patients With Non-Left Main Bifurcation Lesion · NA · not yet recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03590730 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Keimyung University Dongsan Medical Center
- Last refreshed: 19 October 2023
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