NCT03590691: HY-TREC

Conquering Hypertension in Vietnam: Solutions at Grassroots Level

Completed NA Last updated 11 May 2023

What this trial tests

NA trial testing Vietnam National Hypertension Program in Hypertension in 671 participants. Completed in 30 April 2023.

Timeline

7 November 2019

Primary endpoint
31 January 2023

30 April 2023

Quick facts

Lead sponsor	Ministry of Health, Vietnam
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	supportive care
Enrollment	671
Start date	7 November 2019
Primary completion	31 January 2023
Estimated completion	30 April 2023
Sites	1 location across Vietnam

Drugs / interventions tested

• Vietnam National Hypertension Program
• Expanded community health worker services
• Storytelling intervention
• Home blood pressure self-monitoring

Conditions studied

• Hypertension — all drugs for Hypertension →

Sponsor

Ministry of Health, Vietnam

Who can join

25 and older, any sex, with Hypertension. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The objectives of the proposed project are to evaluate the implementation and effectiveness of two multi-faceted community and clinic-based strategies on the control of elevated blood pressure (BP) among adults in Vietnam via a cluster-randomized trial design.

Sixteen communities will be randomized to either an intervention (8 communities) or comparison group (8 communities). Eligible and consenting adult study participants with HTN (n = 680) will be assigned to intervention/comparison status based on the community in which they reside.

Publications & conference data

6 peer-reviewed publications reference this trial (live from Europe PMC):

1. Conquering hypertension in Vietnam-solutions at grassroots level: study protocol of a cluster randomized controlled trial.
   Ha DA, Tran OT, Nguyen HL, Chiriboga G, et al · · 2020 · cited 10× · PMID 33246495 · DOI 10.1186/s13063-020-04917-8
2. Impact of the COVID-19 pandemic on clinical research activities: Survey of study participants and health care workers participating in a hypertension trial in Vietnam.
   Nguyen HL, Tran OT, Ha DA, Phan VH, et al · · 2021 · cited 4× · PMID 34264973 · DOI 10.1371/journal.pone.0253664
3. Lifestyle practices and associated factors among adults with hypertension: Conquering Hypertension in Vietnam-solutions at the grassroots level study.
   Nguyen PH, Goldberg RJ, Allison JJ, Nguyen DB, et al · · 2024 · cited 1× · PMID 38843274 · DOI 10.1371/journal.pone.0303354
4. Health related quality of life among hypertensive adults living in rural Vietnam: Results from a cluster-randomised controlled trial.
   Nguyen CTT, Challagonda J, Ha TS, Nguyen ND, et al · · 2026 · PMID 42127005 · DOI 10.1371/journal.pone.0337817
5. Conquering hypertension in Vietnam: 12- month follow up results from a cluster-randomised controlled trial.
   Nguyen HL, Ha DA, Tran OT, Phan VH, et al · · 2024 · PMID 39045484 · DOI 10.1016/j.lanwpc.2024.101123
6. Conquering Hypertension in Vietnam- Solutions at Grassroots Level: Study Protocol of a Cluster Randomized Controlled Trial
   Ha D, Tran O, Nguyen H, Goldberg R, et al · · 2020 · DOI 10.21203/rs.3.rs-18356/v2