Last reviewed · How we verify

NCT03589053

Limb Remote Ischemic Conditioning and Cerebrovascular Reserve

Status unknown Phase 2 Last updated 9 October 2018
What this trial tests

Phase 2 trial testing Limb remote ischemic conditioning in Ischemic Cerebrovascular Disease in 30 participants. Status unknown.

Timeline
8 October 2018
Primary endpoint
30 December 2018
30 March 2019

Quick facts

Lead sponsorCapital Medical University
PhasePhase 2
StatusStatus unknown
Study typeINTERVENTIONAL
Allocationrandomized
Designparallel
Maskingquadruple
Primary purposetreatment
Enrollment30
Start date8 October 2018
Primary completion30 December 2018
Estimated completion30 March 2019
Sites1 location across China

Drugs / interventions tested

Conditions studied

Sponsor

Capital Medical University

Who can join

Adults 18 to 80, any sex, with Ischemic Cerebrovascular Disease. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Cerebrovascular reserve (CVR), defined as the increase in cerebral blood flow (CBF)in response to a vasodilatory stimulus, is known to reflect the compensative capacity of the brain to maintain adequate blood flow in the face of decreased perfusion due to arterial stenosis. CVR dysfunction has been identified as an independent risk factor for ischemic stroke. Limb remote ischemic preconditioning (LRIC) has been suggested as a protective therapeutic modality against brain ischemia. So it is worth to detect whether LRIC can improve the CVR ability in ischemic cerebrovascular disease patients.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Remote ischaemic conditioning for stroke: unanswered questions and future directions.
    Baig S, Moyle B, Nair KPS, Redgrave J, et al · · 2021 · cited 15× · PMID 33903181 · DOI 10.1136/svn-2020-000722

Verify or expand the search:

Other recruiting trials for Ischemic Cerebrovascular Disease

Currently open trials in the same condition.

Other Capital Medical University trials

Trials by the same sponsor.

Verify against primary sources

Data sources for this page

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03589053.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing