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NCT03589053
Limb Remote Ischemic Conditioning and Cerebrovascular Reserve
Phase 2 trial testing Limb remote ischemic conditioning in Ischemic Cerebrovascular Disease in 30 participants. Status unknown.
30 December 2018
Quick facts
| Lead sponsor | Capital Medical University |
|---|---|
| Phase | Phase 2 |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | quadruple |
| Primary purpose | treatment |
| Enrollment | 30 |
| Start date | 8 October 2018 |
| Primary completion | 30 December 2018 |
| Estimated completion | 30 March 2019 |
| Sites | 1 location across China |
Drugs / interventions tested
- Limb remote ischemic conditioning
- Control group — full drug profile →
Conditions studied
- Ischemic Cerebrovascular Disease — all drugs for Ischemic Cerebrovascular Disease →
Sponsor
Capital Medical University
Who can join
Adults 18 to 80, any sex, with Ischemic Cerebrovascular Disease. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Cerebrovascular reserve (CVR), defined as the increase in cerebral blood flow (CBF)in response to a vasodilatory stimulus, is known to reflect the compensative capacity of the brain to maintain adequate blood flow in the face of decreased perfusion due to arterial stenosis. CVR dysfunction has been identified as an independent risk factor for ischemic stroke. Limb remote ischemic preconditioning (LRIC) has been suggested as a protective therapeutic modality against brain ischemia. So it is worth to detect whether LRIC can improve the CVR ability in ischemic cerebrovascular disease patients.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Remote ischaemic conditioning for stroke: unanswered questions and future directions.
Baig S, Moyle B, Nair KPS, Redgrave J, et al · · 2021 · cited 15× · PMID 33903181 · DOI 10.1136/svn-2020-000722
Verify or expand the search:
- PubMed search for NCT03589053
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Other Capital Medical University trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03589053 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Capital Medical University
- Last refreshed: 9 October 2018
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03589053.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing