NCT03582709

Prospective Cohort Study on Cognition and Cardiovascular Disease of Sedentary Behaviors in Children

ENROLLING BY INVITATION Last updated 11 July 2018

What this trial tests

trial in Sedentary Behavior;Cognition;Cardiovascular-related Disease in 1,000 participants. Enrolling by invitation.

Timeline

1 January 2017

Primary endpoint
31 December 2026

31 December 2026

Quick facts

Lead sponsor	CHEN Yajun
Status	ENROLLING BY INVITATION
Study type	OBSERVATIONAL
Enrollment	1,000
Start date	1 January 2017
Primary completion	31 December 2026
Estimated completion	31 December 2026

Conditions studied

• Sedentary Behavior;Cognition;Cardiovascular-related Disease — all drugs for Sedentary Behavior;Cognition;Cardiovascular-related Disease →

Sponsor

CHEN Yajun

Who can join

Adults 7 to 12, any sex, with Sedentary Behavior;Cognition;Cardiovascular-related Disease. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The prospective cohort study is set up to address research questions dealing with sedentary lifestyle-related events mainly including cognition and cardiovascular-related disease in children .Participants aged 7-12 years old from five primary schools in Guangzhou,Guangdong province will be recruited and followed up to evaluate the risk factors of cognition and cardiovascular-related disease. Objective measurements combined with questionnaire-data-based information on a wide range of lifestyle factors and cognition were applied in this study.

Publications & conference data

8 peer-reviewed publications reference this trial (live from Europe PMC):

1. Association between the 24-hour movement guidelines and executive function among Chinese children.
   Zeng X, Cai L, Yang W, Tan W, et al · · 2022 · cited 20× · PMID 35596171 · DOI 10.1186/s12889-022-13420-5
2. Association between Sugar-Sweetened Beverage Consumption and Executive Function in Children.
   Gui Z, Huang S, Chen Y, Zhao Y, et al · · 2021 · cited 18× · PMID 34960115 · DOI 10.3390/nu13124563
3. Association between weekend catch-up sleep and executive functions in Chinese school-aged children.
   Lv Y, Cai L, Zeng X, Gui Z, et al · · 2020 · cited 14× · PMID 32279704 · DOI 10.5664/jcsm.8494
4. Effects of physical activity and sedentary behaviour on cardiometabolic risk factors and cognitive function in children: protocol for a cohort study.
   Lv Y, Cai L, Gui Z, Zeng X, et al · · 2019 · cited 11× · PMID 31676650 · DOI 10.1136/bmjopen-2019-030322
5. Association between Hyperactivity and SSB Consumption in Schoolchildren: A Cross-Sectional Study in China.
   Zhang Y, Gui Z, Jiang N, Pu X, et al · · 2023 · cited 3× · PMID 36839392 · DOI 10.3390/nu15041034
6. Association Between Dairy Intake and Executive Function in Chinese Children Aged 6-12 Years.
   Zeng X, Cai L, Gui Z, Shen T, et al · · 2022 · cited 3× · PMID 35898711 · DOI 10.3389/fnut.2022.879363
7. Association Between Ideal Cardiovascular Health and Executive Function in Chinese Primary School Children.
   Gui Z, Cai L, Lv Y, Lai L, et al · · 2021 · cited 1× · PMID 35096728 · DOI 10.3389/fpubh.2021.736424
8. Low-fat dairy and yogurt intake are positively associated with general and abdominal obesity among Chinese children: a cross-sectional study.
   Zeng X, Wang Y, Yang WH, Chen YJ, et al · · 2025 · PMID 41350680 · DOI 10.1186/s12889-025-25299-z