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Electroencephalographic Changes in Spinal Cord Stimulation
Spinal cord stimulation by means of an electrode in the back is used to treat patients with persistent chronic pain after back surgery. Based on the stimulation patterns, there are mainly three different technologies available - conventional, burst frequency and the high frequency. It is known that the traditional frequency works through the lateral system of pain pathways in the spinal cord to cause pain reduction. Electroencephalographic(tracing of brain activity) recording of patients using burst have shown an additional effect on an adjacent medial pain pathway which decreases the attention to pain. We want to therefore find out if high frequency stimulation also has an effect on the same pathways. 20 patients who have persistent neuropathic chronic pain after previous spinal surgery, would be eligible to have this treatment as part of their normal care. They will be randomly chosen to undergo a 2 week cycle of high frequency and 2 weeks of burst stimulation. We will record EEG's, pain scores and scores measuring attention to pain and compare findings. All patients will be recruited at the Leeds Pain and Neuromodulaton centre and the EEg analysis will be done by a research team based in Belgium. We hope that the study will improve our understanding of how different stimuation waveforms used for spinal cord stimulation work. We hope to have recruited all 20 patients in a 12 month period.
Details
| Lead sponsor | The Leeds Teaching Hospitals NHS Trust |
|---|---|
| Phase | NA |
| Status | UNKNOWN |
| Enrolment | 18 |
| Start date | Sat Apr 01 2017 00:00:00 GMT+0000 (Coordinated Universal Time) |
| Completion | Sun Dec 01 2019 00:00:00 GMT+0000 (Coordinated Universal Time) |
Conditions
- Pain Management
Interventions
- High Frequency Spinal cord stimulation
- Burst Frequency Spinal cord stimulation
Countries
United Kingdom