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NCT03580018
Intraarticular Injection of Tranexamic Acid Reduced Postoperative Hemarthrosis in Arthroscopic Anterior Cruciate Ligament Reconstruction
NA trial testing Tranexamic Acid Powder in Anterior Cruciate Ligament Reconstruction in 320 participants. Completed in 31 May 2018.
31 May 2018
Quick facts
| Lead sponsor | Taipei Veterans General Hospital, Taiwan |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | single group |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 320 |
| Start date | 1 June 2017 |
| Primary completion | 31 May 2018 |
| Estimated completion | 31 May 2018 |
| Sites | 1 location across Taiwan |
Drugs / interventions tested
- Tranexamic Acid Powder
- Post-anterior cruciate ligament reconstruction (ACLR)
Conditions studied
- Anterior Cruciate Ligament Reconstruction — all drugs for Anterior Cruciate Ligament Reconstruction →
Sponsor
Taipei Veterans General Hospital, Taiwan
Who can join
Adults 20 to 60, any sex, with Anterior Cruciate Ligament Reconstruction. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Post-anterior cruciate ligament reconstruction (ACLR) hemarthrosis may result in increased pain thus delaying postoperative rehabilitation, which may eventually lead to arthrofibrosis and a functional deficit. Many antifibrinolytic agents, including tranexamic acid (TXA), have been used in orthopedic surgeries to reduce postoperative bleeding.The purpose of this study is to evaluate the effect of intra-articular injection of TXA in patients receiving arthroscopic ACLRs. Patients were randomized into two groups. Group 1 patients (TXA group) received the index procedures with a 10 mL intra-articular injection of TXA. Group 2 (control group) patients received the index procedures without TXA injections. An intra-articular suction drain was placed recorded 24 h postoperatively. Clinical evaluations using an IKDC functional score, range of motion (ROM), and a Visual Analogue Scale (VAS) pain score were performed at postoperative day 3 and week 4.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT03580018
- Europe PMC full search
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Related trials
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Trials testing the same drug.
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- NCT05248321 — Precise Delivery of Tranexamic Acid to Enhance Endoscopic Hemostasis for Peptic Ulcer Bleeding · NA · completed
Other recruiting trials for Anterior Cruciate Ligament Reconstruction
Currently open trials in the same condition.
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- NCT06341192 — Comparison Between Combined ALLR With Single Bundle and Double Bundle Anterior Cruciate Ligament Reconstruction · NA · recruiting
- NCT06464705 — To Investigate the Effect of PEMF for Pateitns After Anterior Cruciate Ligament Reconstruction With Hamstring Autograft · NA · recruiting
Other Taipei Veterans General Hospital, Taiwan trials
Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03580018 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Taipei Veterans General Hospital, Taiwan
- Last refreshed: 12 July 2018
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03580018.
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