NCT03579498 (BRAINnHEART) is a clinical trial in Cardiac Arrest, sponsored by Uppsala University.

Who is sponsoring NCT03579498?

NCT03579498 is sponsored by Uppsala University.

What condition does NCT03579498 study?

NCT03579498 studies Cardiac Arrest, Cognitive Function.

Is NCT03579498 still recruiting?

NCT03579498 is currently completed. Last updated 13 April 2026.

Last reviewed 2026-04-13 · How we verify

NCT03579498: BRAINnHEART

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Brain Function After Cardiac Arrest (Measured With FMRI and Cognitive Tests)

Completed Last updated 13 April 2026

What this trial tests

trial in Cardiac Arrest in 48 participants. Completed in 1 November 2023.

Timeline

26 February 2018

Primary endpoint
26 August 2022

1 November 2023

Quick facts

Lead sponsor	Uppsala University
Status	Completed
Study type	OBSERVATIONAL
Enrollment	48
Start date	26 February 2018
Primary completion	26 August 2022
Estimated completion	1 November 2023
Sites	2 locations across Sweden, Norway

Conditions studied

Cardiac Arrest — all drugs for Cardiac Arrest →
Cognitive Function — all drugs for Cognitive Function →

Sponsor

Uppsala University

Who can join

Adults 18 to 70, any sex, with Cardiac Arrest or Cognitive Function. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The aim of this longitudinal study is to determine whether brain function is affected after a cardiac arrest. The primary question is whether cognitive function is affected after cardiac arrest and whether it changes over time (during the first year after the event), compared with a healthy control group. Brain function during cognitive tasks and emotion processing will also be studied using functional MRI (fMRI). Another aim is to study whether clinical outcomes such as PTSD, anxiety and depression can be correlated with cognitive function and whether health- related quality of life is affected after a cardiac arrest. The results from the cardiac arrest patient group will be compared with a healthy control group.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Long Term Cognitive Function After Cardiac Arrest: A Mini-Review.
Hagberg G, Ihle-Hansen H, Sandset EC, Jacobsen D, et al · · 2022 · cited 15× · PMID 35721022 · DOI 10.3389/fnagi.2022.885226

Verify or expand the search:

Other recruiting trials for Cardiac Arrest

Currently open trials in the same condition.

NCT07239206 — Serious Game for Improving Targeted Temperature Management Knowledge and Situational Awareness in Critical Care Nurses · NA · recruiting
NCT06780722 — Study of the Occurrence of Cardiocirculatory Arrest as a Function of the Level of Hypoxemia During a Maastricht 3 Proced · recruiting
NCT06405581 — The Impact of Frailty on Cardiopulmonary Resuscitation Adverse Outcomes in Patients Requiring Code Blue Activation · recruiting
NCT06511999 — Continuous Jugular Venous Oxygen Saturation (SjO2) Measurement After Cardiac Arrest · recruiting
NCT07113769 — Plasma Biomarkers and Platelet Morphology of Extracorporeal CardioPulmonary Resuscitation · recruiting

Other Uppsala University trials

Trials by the same sponsor.

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NCT07351149 — Postoperative Acute Kidney Injury in Children Undergoing Major Non-cardiac Surgery · recruiting
NCT07461636 — Robotic-Assisted Pedicle Screw Placement in Spine Surgery · recruiting
NCT07273409 — Pancreatic Neuroendocrine Tumour - Optimal Surgical Debulking or Not · NA · recruiting
NCT07352683 — Open TAP-block in Pediatric Abdominal Surgery · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03579498 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Uppsala University
Last refreshed: 13 April 2026

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03579498.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing