NCT03577912

Efficacy of Transversus Abdominis Plane (TAP) Block Techniques: Surgeon vs Anesthesia - Ultrasound Guidance

Completed NA Last updated 17 September 2018

What this trial tests

NA trial testing TAP block administered by Surgery in Post Operative Analgesia in 60 participants. Completed in 31 July 2018.

Timeline

17 August 2015

Primary endpoint
12 April 2018

31 July 2018

Quick facts

Lead sponsor	Beth Israel Deaconess Medical Center
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	triple
Primary purpose	treatment
Enrollment	60
Start date	17 August 2015
Primary completion	12 April 2018
Estimated completion	31 July 2018
Sites	1 location across United States

Drugs / interventions tested

• TAP block administered by Surgery
• TAP block administered by Anesthesia

Conditions studied

• Post Operative Analgesia — all drugs for Post Operative Analgesia →
• Non-inferiority Trial — all drugs for Non-inferiority Trial →

Sponsor

Beth Israel Deaconess Medical Center

Who can join

18 and older, any sex, with Post Operative Analgesia or Non-inferiority Trial. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The transversus abdominis plane (TAP) block is a regional anesthesia technique where local anesthetic is injected into the neurovascular plane between the transversus abdominis and internal oblique muscles. The TAP block has been shown to provide postoperative analgesia following abdominal surgery.There are many methods to administer local anesthetic into the transversus abdominus plane to provide post-operative analgesia. The more prevalent method is for an anesthesia provider to inject local anesthetic into the plane using ultrasound guidance, before surgery or after the conclusion of surgery. Alternatively, a surgeon can administer the local anesthetic during the operation without additional time or expense using direct laparoscopic visualization. We propose to compare the two methods for non-inferiority, in the context of an established enhanced recovery after surgery (ERAS) program. Non-inferiority being established by no demonstrable difference in post-operative narcotic requirements and equivalent average pain scores.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

1. Surgeon-delivered laparoscopic transversus abdominis plane blocks are non-inferior to anesthesia-delivered ultrasound-guided transversus abdominis plane blocks: a blinded, randomized non-inferiority trial.
   Wong DJ, Curran T, Poylin VY, Cataldo TE. · · 2020 · cited 30× · PMID 31485929 · DOI 10.1007/s00464-019-07097-y