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NCT03576391
The Influence of Fatigue on Trunk Motor Control and Brain Activity
NA trial testing Control condition in Muscle Fatigue in 22 participants. Completed in 24 February 2018.
24 February 2018
Quick facts
| Lead sponsor | University Ghent |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | crossover |
| Masking | single |
| Primary purpose | basic science |
| Enrollment | 22 |
| Start date | 15 September 2016 |
| Primary completion | 24 February 2018 |
| Estimated completion | 24 February 2018 |
| Sites | 1 location across Belgium |
Drugs / interventions tested
- Control condition
- Rapid Arm Movements
- Physical fatigue condition
- Cognitive fatigue condition
Conditions studied
- Muscle Fatigue — all drugs for Muscle Fatigue →
- Mental Fatigue — all drugs for Mental Fatigue →
- Event-related Potentials — all drugs for Event-related Potentials →
Sponsor
University Ghent
Who can join
Adults 18 to 45, any sex, with Muscle Fatigue or Mental Fatigue. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
This study aims at examining the influence of both physically and cognitively induced fatigue on trunk motor control on the one hand and brain activity related to movement preparation on the other hand, in healthy adult subjects. Furthermore, a comparison between the effects of both types of fatigue will be made. For this purpose a motor control task will be performed and compared before and after 3 specific interventions: i.e. a control intervention, a physical task and a cognitive task. Muscle and brain activity will be measured during each motor control task. It is hypothesised that motor control will not be altered after a control task, i.e. seated rest for 45 minutes. With regards to the physical fatigue condition, it is expected that trunk muscles will contract earlier after this task than before due to altered motor control. Cognitive fatigue is hypothesised to have similar underlying processes as physical fatigue, thus a similar earlier muscle contraction is also expected after cognitive fatigue. Lastly, as both types of fatigue are expected to induce a similar effect on motor control no significant differences between cognitive and physical fatigue are hypothesised. However, it is possible that the magnitude of this effect differs between types of fatigue, i.e. that 1 of both types has a bigger effect on motor control than the other. With regards to brain activity in preparation of a motor control task similar hypotheses are formulated: no effect of the control task on brain activity, earlier and possibly increased brain activity after both fatiguing tasks, and no differences between both types of fatigue besides a possible difference in magnitude of effect.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT03576391
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03576391 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by University Ghent
- Last refreshed: 18 December 2023
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03576391.
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