Last reviewed · How we verify
NCT03575312: EnroHuman
Pharmacokinetics of Enrofloxacin in Plasma and Urine
NA trial testing Enrofloxacin in Healthy in 6 participants. Completed in 30 August 2018.
4 June 2018
Quick facts
| Lead sponsor | Fraunhofer-Institute of Toxicology and Experimental Medicine |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | basic science |
| Enrollment | 6 |
| Start date | 27 April 2018 |
| Primary completion | 4 June 2018 |
| Estimated completion | 30 August 2018 |
| Sites | 1 location across Germany |
Drugs / interventions tested
- Enrofloxacin (ENROFLOXACIN) — full drug profile →
Conditions studied
- Healthy — all drugs for Healthy →
Sponsor
Fraunhofer-Institute of Toxicology and Experimental Medicine
Who can join
Adults 18 to 55, male only, with Healthy. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Antibiotics like enrofloxacin are widely used in animal farming to treat and prevent bacterial infections. A previous study in poultry farms has shown that yardmen show significant concentrations of administered antibiotics in their urine. It is currently unclear how poultry yardmen are exposed to the administered antibiotics. The objective of this exemplarily study is to obtain information on the pharmacokinetics of the different uptake routes (oral, inhaled or dermal).
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Effect of four fluoroquinolones on the viability of bladder cancer cells in 2D and 3D cultures.
Kloskowski T, Fekner Z, Szeliski K, Paradowska M, et al · · 2023 · cited 6× · PMID 37534254 · DOI 10.3389/fonc.2023.1222411
Verify or expand the search:
- PubMed search for NCT03575312
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03575312 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Fraunhofer-Institute of Toxicology and Experimental Medicine
- Last refreshed: 12 December 2018
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03575312.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing