Who is sponsoring NCT03573427?

NCT03573427 is sponsored by Jaimie Manlucu.

What drugs are being tested in NCT03573427?

Interventions in NCT03573427: Trans-atrial septal placement LV lead for CRT.

What condition does NCT03573427 study?

NCT03573427 studies Heart Failure，Congestive, Left Ventricular Dysfunction, Left Bundle-Branch Block.

Is NCT03573427 still recruiting?

NCT03573427 is currently withdrawn. Last updated 24 July 2019.

Last reviewed 2019-07-24 · How we verify

NCT03573427: EndoCRT

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

LV Endocardial CRT for Patients With Intermediate QRS Width

Withdrawn Last updated 24 July 2019

What this trial tests

trial testing Trans-atrial septal placement LV lead for CRT in Heart Failure，Congestive. Withdrawn.

Timeline

28 April 2016

Primary endpoint
28 April 2019

22 July 2019

Quick facts

Lead sponsor	Jaimie Manlucu
Status	Withdrawn
Study type	OBSERVATIONAL
Start date	28 April 2016
Primary completion	28 April 2019
Estimated completion	22 July 2019
Sites	8 locations across Canada

Drugs / interventions tested

Trans-atrial septal placement LV lead for CRT

Conditions studied

Heart Failure，Congestive — all drugs for Heart Failure，Congestive →
Left Ventricular Dysfunction — all drugs for Left Ventricular Dysfunction →
Left Bundle-Branch Block — all drugs for Left Bundle-Branch Block →

Sponsor

Jaimie Manlucu

Who can join

Eligibility, any sex, with Heart Failure，Congestive or Left Ventricular Dysfunction. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This pilot study is designed as a multi-centre cohort study determining the degree of LV reverse remodeling in patients with intermediate QRS widths (120-149ms) who undergo CRT implant with transseptal LV leads, and comparing to the average expected reverse remodeling rate in patients with standard transvenous coronary sinus leads and QRS widths ≥150ms.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

The Memory of the Heart.
Cirillo M. · · 2018 · cited 2× · PMID 30423868 · DOI 10.3390/jcdd5040055

Verify or expand the search:

Other recruiting trials for Heart Failure，Congestive

Currently open trials in the same condition.

NCT06819618 — Prediction of Heart-Failure with Machine Learning · recruiting
NCT06350695 — The ROle of Compression StocKings in Heart Failure Patients · NA · recruiting
NCT06176131 — The Cardio-share Telemedicine Cross-sector Collaboration Model for Managing Vulnerable Patients With Heart Failure · recruiting
NCT06324682 — ConTempoRary Cardiac Stimulation in Clinical practicE: lEft, BivEntriculAr, Right, and conDuction System Pacing · recruiting
NCT04179643 — AB-1002 in Patients With Class III Heart Failure · Phase 1 · active not recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03573427 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Jaimie Manlucu
Last refreshed: 24 July 2019

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03573427.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing