Comparison of Therapy in Treatment of Patients With Helicobacter Pylori Infection: Concomitant Versus Hybrid Therapy.

NCT03572777 NA COMPLETED

The aim of the study is to compare the effectiveness of two therapeutic protocols in the treatment of Helicobacter pylori infection. The hypothesis of our research is that the two therapeutic options (hybrid and concomitant therapy) will be equally successful in the treatment of Helicobacter pylori infection. In other words, in both therapeutic groups we expect successful treatment of Helicobacter pylori infection in or more than 90 % of patients. In other studies, both therapeutic options have the same efficacy in treating H. pylori infection. On the other had there are no studies available in Croatia to compare the effectiveness of these therapeutic options so far, which is the main objective of our research. The secondary goals of our study will be: the existence of differences in the occurrence of possible side effects, as well as the compliance between patients in both therapeutic options. It is also our aim to compare the quality of life of patients with Helicobacter pylori infection before and after treatment, via a questionnaire that is common for this purpose. The study is expected to include a total of 120 patients (60 patients in each therapy group), and the planned duration is 12 months.

Details

Lead sponsor	Antonio Mestrovic
Phase	NA
Status	COMPLETED
Enrolment	159
Start date	Sun Apr 15 2018 00:00:00 GMT+0000 (Coordinated Universal Time)
Completion	Tue Oct 15 2019 00:00:00 GMT+0000 (Coordinated Universal Time)

Conditions

• Helicobacter Pylori Infection

Interventions

• Concomitant therapy
• Concomitant therapy
• Concomitant therapy
• Concomitant therapy
• Hybrid therapy
• Hybrid therapy
• Hybrid therapy
• Hybrid therapy

Countries

Croatia