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NCT03570060: SAFAS

Stepwise Screening for Silent Atrial Fibrillation After Stroke

Completed Last updated 25 June 2024
What this trial tests

trial testing Blood sample in Ischemic Cerebrovascular Accident in 264 participants. Completed in 23 March 2023.

Timeline
1 April 2018
Primary endpoint
23 March 2023
23 March 2023

Quick facts

Lead sponsorCentre Hospitalier Universitaire Dijon
StatusCompleted
Study typeOBSERVATIONAL
Enrollment264
Start date1 April 2018
Primary completion23 March 2023
Estimated completion23 March 2023
Sites1 location across France

Drugs / interventions tested

Conditions studied

Sponsor

Centre Hospitalier Universitaire Dijon

Who can join

18 and older, any sex, with Ischemic Cerebrovascular Accident. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The main hypothesis of this work is that an approach combining clinical parameters and biomarker assays could improve the understanding and prediction of the occurrence of silent atrial fibrillation (AF) in the acute phase after stroke. In this prospective work, the investigators will rely on the Dijon Stroke Registry, which collects extensive clinical data for each patient hospitalized for a stroke. As part of this registry, patients are seen 6 months after stroke to assess their clinical status. This clinical follow-up will allow us to judge the evolution of the AF diagnosed during the acute episode at a distance.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

  1. Multimodal Approach for the Prediction of Atrial Fibrillation Detected After Stroke: SAFAS Study.
    Garnier L, Duloquin G, Meloux A, Benali K, et al · · 2022 · cited 18× · PMID 35911547 · DOI 10.3389/fcvm.2022.949213
  2. Distribution of atrial cardiomyopathy markers and association with atrial fibrillation detected after ischaemic stroke in the SAFAS study.
    Didier R, Garnier L, Duloquin G, Meloux A, et al · · 2024 · cited 12× · PMID 37429637 · DOI 10.1136/svn-2023-002447

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