NCT03569605: IMPACT

Promoting Physical Activity in Young Adult Cancer Survivors Using mHealth and Adaptive Tailored Feedback Strategies

Completed NA Last updated 1 April 2021

What this trial tests

NA trial testing Self-help in Physical Activity in 280 participants. Completed in 29 January 2021.

Timeline

23 August 2018

Primary endpoint
29 January 2021

29 January 2021

Quick facts

Lead sponsor	UNC Lineberger Comprehensive Cancer Center
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	supportive care
Enrollment	280
Start date	23 August 2018
Primary completion	29 January 2021
Estimated completion	29 January 2021
Sites	1 location across United States

Drugs / interventions tested

• Self-help
• Intervention

Conditions studied

• Physical Activity — all drugs for Physical Activity →
• Neoplasms — all drugs for Neoplasms →
• Neoplasms by Site — all drugs for Neoplasms by Site →
• Cancer — all drugs for Cancer →

Sponsor

UNC Lineberger Comprehensive Cancer Center — full company profile →

Who can join

Adults 18 to 39, any sex, with Physical Activity or Neoplasms. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

To date, few interventions have been designed specifically to promote physical activity in young adult cancer survivors, nor used novel technologies for delivery; none have been successful in promoting long-term adherence to PA. The purpose of this randomized controlled trial is to test the efficacy of a theory-based, mobile physical activity intervention with adaptive goal-setting and tailored feedback that is aimed at increasing physical activity among young adult cancer survivors.

Publications & conference data

7 peer-reviewed publications reference this trial (live from Europe PMC):

1. Effect of an mHealth intervention on physical activity outcomes among young adult cancer survivors: The IMPACT randomized controlled trial.
   Valle CG, Diamond MA, Heiling HM, Deal AM, et al · · 2023 · cited 28× · PMID 36444676 · DOI 10.1002/cncr.34556
2. Recruitment of young adult cancer survivors into a randomized controlled trial of an mHealth physical activity intervention.
   Valle CG, Camp LN, Diamond M, Nezami BT, et al · · 2022 · cited 16× · PMID 35379294 · DOI 10.1186/s13063-022-06148-5
3. Promoting physical activity in young adult cancer survivors using mHealth and adaptive tailored feedback strategies: Design of the Improving Physical Activity after Cancer Treatment (IMPACT) randomized controlled trial.
   Valle CG, Pinto BM, LaRose JG, Diamond M, et al · · 2021 · cited 15× · PMID 33515784 · DOI 10.1016/j.cct.2021.106293
4. Physical activity maintenance among young adult cancer survivors in an mHealth intervention: Twelve-month outcomes from the IMPACT randomized controlled trial.
   Valle CG, Diamond MA, Heiling HM, Deal AM, et al · · 2023 · cited 8× · PMID 37317660 · DOI 10.1002/cam4.6238
5. The usage of population and disease registries as pre-screening tools for clinical trials, a systematic review.
   Foucher J, Azizi L, Öijerstedt L, Kläppe U, et al · · 2024 · cited 1× · PMID 38654383 · DOI 10.1186/s13643-024-02533-0
6. Disentangling Positive Affect Heterogeneity in a Digital Physical Activity Intervention for Young Adult Cancer Survivors: A Group-Based Multi-Trajectory Modeling Approach.
   Choi SM, Willis EA, Smitherman AB, Martin SL, et al · · 2026 · PMID 42133893 · DOI 10.1002/pon.70484
7. Examining sociodemographic and health-related characteristics as moderators of an mHealth intervention on physical activity outcomes in young adult cancer survivors.
   Valle CG, Heiling HM, Deal AM, Diamond MA, et al · · 2025 · PMID 38607515 · DOI 10.1007/s11764-024-01577-4