NCT03562715 is a clinical trial in Preeclampsia, sponsored by Cairo University.

Who is sponsoring NCT03562715?

NCT03562715 is sponsored by Cairo University.

What condition does NCT03562715 study?

NCT03562715 studies Preeclampsia.

Is NCT03562715 still recruiting?

NCT03562715 is currently completed. Last updated 19 June 2018.

Last reviewed 2018-06-19 · How we verify

NCT03562715

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

microRNAs Role in Pre-eclampsia Diagnosis

Completed Last updated 19 June 2018

What this trial tests

trial in Preeclampsia in 200 participants. Completed in 25 December 2017.

Timeline

28 November 2016

Primary endpoint
15 June 2017

25 December 2017

Quick facts

Lead sponsor	Cairo University
Status	Completed
Study type	OBSERVATIONAL
Enrollment	200
Start date	28 November 2016
Primary completion	15 June 2017
Estimated completion	25 December 2017

Conditions studied

Preeclampsia — all drugs for Preeclampsia →

Sponsor

Cairo University

Who can join

Adults 23 to 35, female only, with Preeclampsia. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Pre-eclampsia is one of the most threatening pregnancy complications. So far neither a secure, competent therapy for PE nor effective biomarkers for a premature discovery has been achieved.The aim of our study was to identify miRNAs 136, 494 and 495 genes expression in exosomes of peripheral blood compared to umbilical cord mesenchymal stem cells conditioned media released exososomes in patients with PE, as valuable markers for PE early prediction.

Publications & conference data

8 peer-reviewed publications reference this trial (live from Europe PMC):

Exosomes from mesenchymal stem/stromal cells: a new therapeutic paradigm.
Yin K, Wang S, Zhao RC. · · 2019 · cited 290× · PMID 30992990 · DOI 10.1186/s40364-019-0159-x
Potential Use of Exosomes as Diagnostic Biomarkers and in Targeted Drug Delivery: Progress in Clinical and Preclinical Applications.
Huda MN, Nafiujjaman M, Deaguero IG, Okonkwo J, et al · · 2021 · cited 160× · PMID 33988964 · DOI 10.1021/acsbiomaterials.1c00217
Mesenchymal stem/stromal cell-derived exosomes in regenerative medicine and cancer; overview of development, challenges, and opportunities.
Hassanzadeh A, Rahman HS, Markov A, Endjun JJ, et al · · 2021 · cited 141× · PMID 34020704 · DOI 10.1186/s13287-021-02378-7
Mesenchymal stem cell-derived exosome: a promising alternative in the therapy of Alzheimer's disease.
Guo M, Yin Z, Chen F, Lei P. · · 2020 · cited 134× · PMID 32928293 · DOI 10.1186/s13195-020-00670-x
Clinical applications for exosomes: Are we there yet?
Perocheau D, Touramanidou L, Gurung S, Gissen P, et al · · 2021 · cited 101× · PMID 33751579 · DOI 10.1111/bph.15432
New therapeutic approaches of mesenchymal stem cells-derived exosomes.
Janockova J, Slovinska L, Harvanova D, Spakova T, et al · · 2021 · cited 98× · PMID 34030679 · DOI 10.1186/s12929-021-00736-4
The potential use of mesenchymal stem cells-derived exosomes as microRNAs delivery systems in different diseases.
Oveili E, Vafaei S, Bazavar H, Eslami Y, et al · · 2023 · cited 81× · PMID 36690996 · DOI 10.1186/s12964-022-01017-9
Exosomes: Their Role in Pathogenesis, Diagnosis and Treatment of Diseases.
Aheget H, Mazini L, Martin F, Belqat B, et al · · 2020 · cited 75× · PMID 33396739 · DOI 10.3390/cancers13010084

Verify or expand the search:

Other recruiting trials for Preeclampsia

Currently open trials in the same condition.

NCT06953115 — Vagal Stimulation Therapy and Preeclampsia · NA · recruiting
NCT06333652 — Ravulizumab in Pregnancies Complicated by Severe Hypertensive Disorders · Phase 2 · recruiting
NCT07282171 — A Study to Investigate the Safety, Pharmacodynamic and Pharmacokinetic Characteristics of CBP-4888 in Hospitalized Parti · Phase 1 · recruiting
NCT07345845 — MR and Inflammation After Preeclampsia · EARLY_PHASE1 · active not recruiting
NCT07041281 — Spironolactone to Improve Pregnancy-Associated Hypertension Trajectories · Phase 2 · recruiting

Other Cairo University trials

Trials by the same sponsor.

NCT04155528 — Effect of Music Therapy on Postoperative Health Outcomes · NA · not yet recruiting
NCT07363239 — CBCT-Based Safety Distance for Implant Placement Near the Inferior Alveolar Canal · not yet recruiting
NCT07374575 — Egyptian Dental Professionals' Perspectives on the Oral Microbiome and Exosomes · not yet recruiting
NCT07381153 — In-Vitro Cytotoxicity Assessment of INOX (Nanoksa G Plus) Polymer Discs · not yet recruiting
NCT07375394 — 3D-Printed Extraoral Camera for Standardized Dental Photography · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03562715 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Cairo University
Last refreshed: 19 June 2018

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03562715.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing