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NCT03562325
ACT for ME/CFS - an Open Case Trial
NA trial testing Acceptance and Commitment Therapy (ACT) in Chronic Fatigue Syndrome in 40 participants. Completed in 31 October 2017.
31 October 2017
Quick facts
| Lead sponsor | Rikard Wicksell |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | na |
| Design | single group |
| Masking | none |
| Primary purpose | treatment |
| Enrollment | 40 |
| Start date | 10 November 2012 |
| Primary completion | 31 October 2017 |
| Estimated completion | 31 October 2017 |
| Sites | 1 location across Sweden |
Drugs / interventions tested
- Acceptance and Commitment Therapy (ACT)
Conditions studied
- Chronic Fatigue Syndrome — all drugs for Chronic Fatigue Syndrome →
Sponsor
Rikard Wicksell
Who can join
18 and older, any sex, with Chronic Fatigue Syndrome. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The goal of this research project is to evaluate if our well-researched behavior medicine treatment model for chronic pain, based on Acceptance and Commitment Therapy, is safe and effective in increasing quality of life and functioning also in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). To date there are no effective treatments for ME/CFS as the ethology and pathophysiology are unknown, while levels of functioning and quality of life as well as secondary effects such as depressive and anxiety symptoms indicate a highly affected patient population. As such, there is a need for behavior medicine approaches that aim to alleviate suffering and promote increases in quality of life for these patients. The aim of the present study is to do a preliminary evaluation of the safety, acceptability and efficacy of an ACT-based treatment protocol for ME/CFS. An additional aim is to explore potential mediators of change for the effect of treatment on disability.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Application of acceptance and commitment therapy in cancer-related fatigue management: insights from clinical trials and future perspectives.
Chen X, Li Z. · · 2025 · cited 1× · PMID 39964319 · DOI 10.1097/js9.0000000000002305
Verify or expand the search:
- PubMed search for NCT03562325
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Acceptance and Commitment Therapy (ACT)
Trials testing the same drug.
- NCT06704061 — Online Yoga vs Acceptance and Commitment Therapy for Treating Chronic Musculoskeletal Pain · NA · recruiting
- NCT07066488 — Brief ACT Intervention for Problem Gambling: A Pilot Study · NA · not yet recruiting
- NCT07175402 — Feasibility and Acceptability of an Online ACT Intervention for Disorders of Gut-Brain Interaction - Beta Trial · NA · completed
- NCT06887751 — Feasibility and Acceptability of an Online ACT Intervention for Disorders of Gut-Brain Interaction · NA · completed
- NCT07256093 — The Effectiveness of Acceptance and Commitment Therapy (ACT) on Dysfunctional Attitudes and Difficulties in Emotion Regu · NA · completed
Other recruiting trials for Chronic Fatigue Syndrome
Currently open trials in the same condition.
- NCT07009691 — Hydrogen Water Intervention With Heart Rate Variability as an Outcome Biomarker in ME/CFS · NA · recruiting
- NCT06585254 — tVNS in Long COVID-19 · NA · recruiting
- NCT05741112 — The Long COVID-19 Wearable Device Study · NA · recruiting
- NCT05967052 — Investigation of Treating Chronic Fatigue Syndrome After COVID With Pharmacotherapy (Pregabalin) or Complex Rehabilitati · Phase 2 · recruiting
- NCT05525598 — Internet-based Treatment for Patients Suffering From Severe Functional Somatic Disorders · NA · recruiting
Other Rikard Wicksell trials
Trials by the same sponsor.
- NCT03344926 — Smart Phone ACT Treatment for Adults With Longstanding Pain - a Pilot Study · NA · completed
- NCT03105908 — Internet-delivered ACT for Chronic Pain · NA · completed
- NCT03272893 — Biomarkers in Pain and Pain Treatment · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03562325 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Rikard Wicksell
- Last refreshed: 19 June 2018
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03562325.
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