Who is sponsoring NCT03554876?

NCT03554876 is sponsored by Fundación Eduardo Anitua.

What drugs are being tested in NCT03554876?

Interventions in NCT03554876: Multi-Im Machined transepithelial component., Multi-Im Nanogolden transepithelial component, Multi-Im Ti-Golden transepithelial component.

What condition does NCT03554876 study?

NCT03554876 studies Biofilm Formation.

Is NCT03554876 still recruiting?

NCT03554876 is currently completed. Last updated 25 February 2025.

Last reviewed 2025-02-25 · How we verify

NCT03554876

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Randomized and Controlled Clinical Trial to Evaluate Bacterial Adhesion on Multi-Im® Transepithelial Components

Completed NA Last updated 25 February 2025

What this trial tests

NA trial testing Multi-Im Machined transepithelial component. in Biofilm Formation in 17 participants. Completed in 22 December 2020.

Timeline

16 July 2018

Primary endpoint
22 December 2020

22 December 2020

Quick facts

Lead sponsor	Fundación Eduardo Anitua
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	single
Primary purpose	treatment
Enrollment	17
Start date	16 July 2018
Primary completion	22 December 2020
Estimated completion	22 December 2020
Sites	1 location across Spain

Drugs / interventions tested

Multi-Im Machined transepithelial component.
Multi-Im Nanogolden transepithelial component
Multi-Im Ti-Golden transepithelial component

Conditions studied

Biofilm Formation — all drugs for Biofilm Formation →

Sponsor

Fundación Eduardo Anitua — full company profile →

Who can join

18 and older, any sex, with Biofilm Formation. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This study evaluates the efficacy of Mutli-Im® transepithelial components in the inhibition of bacterial adhesion. The control group will be the Multi-Im® transepithelial component with the conventional surface (Multi-IM® Machined) and the experimental group will be the Multi-Im transepithelial components with the Ti-Golden® surface (Multi-Im Golden) or with the nanogolden surface (Multi-Im® nanogolden). Periodontal indices and biofilformation will be assessed during 2 months after implant loading. Metagenomic analysis and PCR technique will be implemented to assess the biofilm formation.

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

Nanotechnology in combating biofilm: A smart and promising therapeutic strategy.
Mohanta YK, Chakrabartty I, Mishra AK, Chopra H, et al · · 2022 · cited 58× · PMID 36938129 · DOI 10.3389/fmicb.2022.1028086
Assessing peri-implant bacterial community structure: the effect of microbiome sample collection method.
Anitua E, Murias-Freijo A, Tierno R, Tejero R, et al · · 2024 · cited 3× · PMID 39187802 · DOI 10.1186/s12903-024-04675-y
Effect of implant abutment surface treatments on bacterial biofilm composition and structure.
Anitua E, Murias-Freijo A, Tierno R, Tejero R, et al · · 2025 · PMID 39916977 · DOI 10.1080/20002297.2025.2459922

Verify or expand the search:

Other Fundación Eduardo Anitua trials

Trials by the same sponsor.

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NCT04929743 — Randomized Clinical Trial to Evaluate the Predictability of 5.5 mm Dental Implants · NA · completed
NCT04945629 — Plasma Rich in Growth Factors in the Preservation of the Alveolar Ridge After Simple Molar Tooth Extractions. · Phase 3 · completed
NCT04543292 — Clinical Evaluation of Polytetrafluoroethylene (PTFE, MATFILL) for the Sealing of Prosthetic Chimneys. · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03554876 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Fundación Eduardo Anitua
Last refreshed: 25 February 2025

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03554876.

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