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Tobacco and Sperm Genome: Effects of Smoking Cessation (TABAGERM)
Tobacco is a male infertility risk factor. Many studies comparing smokers to non-smokers have shown effects on spermatogenesis and the quality of the male gamete. In vitro fertilization success rates are decreased in smokers and in natural procreation the time required to conceive (excellent fertility indicator) seems to be lengthened in the smoker. The prospective study that the investigators propose to carry out would make it possible to know the time required for the repair of the sperm abnormalities and in particular the DNA of the gametes generated by the smoking.
Details
| Lead sponsor | University Hospital, Toulouse |
|---|---|
| Phase | NA |
| Status | COMPLETED |
| Enrolment | 25 |
| Start date | Tue Oct 02 2018 00:00:00 GMT+0000 (Coordinated Universal Time) |
| Completion | Tue Jun 21 2022 00:00:00 GMT+0000 (Coordinated Universal Time) |
Conditions
- Male Infertility
Interventions
- Fragmented DNA evaluation in blood and semen samples
Countries
France