NCT03551145 is a Phase 4 clinical trial of Acellular collagen matrix in Peri-Implantitis, sponsored by Universidad Complutense de Madrid.

Who is sponsoring NCT03551145?

NCT03551145 is sponsored by Universidad Complutense de Madrid.

What drugs are being tested in NCT03551145?

Interventions in NCT03551145: Acellular collagen matrix, Autogenous free gingival graft.

What condition does NCT03551145 study?

NCT03551145 studies Peri-Implantitis.

Is NCT03551145 still recruiting?

NCT03551145 is currently status unknown. Last updated 11 June 2018.

Last reviewed 2018-06-11 · How we verify

NCT03551145

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Patient Perception and Clinical Efficacy of a Collagen Matrix for the Treatment of Peri-implantitis

Status unknown Phase 4 Last updated 11 June 2018

What this trial tests

Phase 4 trial testing Acellular collagen matrix in Peri-Implantitis in 50 participants. Status unknown.

Timeline

1 February 2017

Primary endpoint
1 December 2019

1 March 2020

Quick facts

Lead sponsor	Universidad Complutense de Madrid
Phase	Phase 4
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	treatment
Enrollment	50
Start date	1 February 2017
Primary completion	1 December 2019
Estimated completion	1 March 2020
Sites	1 location across Spain

Drugs / interventions tested

Acellular collagen matrix
Autogenous free gingival graft

Conditions studied

Peri-Implantitis — all drugs for Peri-Implantitis →

Sponsor

Universidad Complutense de Madrid — full company profile →

Who can join

18 and older, any sex, with Peri-Implantitis. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This is a multi-centre, randomized clinical trial which evaluates the efficiency of the collagen xenograft (Muco-Graft®) in comparison to the autologous connective tissue graft for the augmentation of keratinized mucosa and gaining hygienic access to the implants diagnosed with peri-implantitis.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Surgical Treatment of Peri-Implantitis Combined With Keratinized Mucosa Augmentation: Results of a Dual-Center 3-Year RCT.
Solonko M, Regidor E, Ortiz-Vigón A, Montero E, et al · · 2025 · PMID 40542468 · DOI 10.1111/clr.14465

Verify or expand the search:

Other recruiting trials for Peri-Implantitis

Currently open trials in the same condition.

NCT07012915 — Immunological-Clinical Evaluation of the Etiopathogenesis of Peri-Implantitis · NA · recruiting
NCT06679283 — Surgical Treatment of Peri-implantitis With Adjunctive Application of Platelet Rich Fibrin (PRF) · NA · recruiting
NCT06017817 — Antibacterial Photodynamic Therapy in the Management of Peri-implantitis · NA · recruiting
NCT06364982 — Distance Between Dental Implants as a Risk Indicator for Peri-implant Disease. · recruiting
NCT06288919 — Erythritol vs Ultrasonic Scaler Prophylaxis Systems on Dental Implants With Crowns Made by Different Materials · NA · active not recruiting

Other Universidad Complutense de Madrid trials

Trials by the same sponsor.

NCT07361848 — Long-Hold Yielding Isometric Exercise for Patellar Tendinopathy in Weightlifting Athletes · NA · not yet recruiting
NCT07273006 — Percutaneous Electrical Nerve Stimulation As Alternative To Nerve Blocks In Anesthesia, Pain Medicine And Rehabilitation · Phase 4 · not yet recruiting
NCT07527351 — ANALYSIS OF THE RELIABILITY AND VALIDITY OF LASER SPECKLE CONTRAST IMAGING · NA · recruiting
NCT07484620 — Physical Activity and Fitness in Pediatric Inflammatory Bowel Disease · NA · not yet recruiting
NCT07485400 — Aerobic Interval vs Continuous Training on Heart Rate-Power Decoupling in Ischemic Heart Disease · NA · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03551145 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Universidad Complutense de Madrid
Last refreshed: 11 June 2018

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03551145.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing