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Using DNA-Typing and Erythrocyte Microparticle Analysis to Detect Homologous/Autologous Blood Doping- a Transfusion Study
A total of 12 subjects will be recruited for participation in this study. 6 subjects will receive re-infusion of autologous blood, and 6 subjects (anemic patients) will receive a homologous transfusion.
Details
| Lead sponsor | Hamad Medical Corporation |
|---|---|
| Phase | Phase 3 |
| Status | UNKNOWN |
| Enrolment | 12 |
| Start date | 2018-09-20 |
| Completion | 2021-12 |
Conditions
- Blood Disease
- Blood Transfusion, Autologous
- Blood Doping
- Blood Transfusion, Homologous
Interventions
- Homologous Blood Transfusion
- Autologous Blood Transfusion
Primary outcomes
- Donor DNA (# of loci with triplets or quadruplets): — 12 months
Clearance Kinetics of donor DNA which is transferred during the transfusion of one bag of homologous blood will be established. - Cellular Microparticles (10^3/uL): — 12 months
Clearance Kinetics of cellular microparticles which are introduced during an autologous blood transfusion and are originating from red blood cells during blood storage will be established.
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