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NCT03546179
Tidal Volume Challenge and Reliability of Plethysmography Variability Index
trial testing tidal volume challenge test in Abdominal Cancer in 48 participants. Completed in 15 February 2020.
15 January 2020
Quick facts
| Lead sponsor | Fayoum University Hospital |
|---|---|
| Status | Completed |
| Study type | OBSERVATIONAL |
| Enrollment | 48 |
| Start date | 1 August 2018 |
| Primary completion | 15 January 2020 |
| Estimated completion | 15 February 2020 |
| Sites | 1 location across Egypt |
Drugs / interventions tested
- tidal volume challenge test
- Volume loading — full drug profile →
Conditions studied
- Abdominal Cancer — all drugs for Abdominal Cancer →
Sponsor
Fayoum University Hospital
Who can join
18 and older, any sex, with Abdominal Cancer. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The aim of this study is to investigate whether a temporary increase in tidal volume can predict fluid responsiveness in patients receiving a low tidal volume ventilation in hepatobiliary and pancreatic surgeries. The hypothesis of this study is that a temporary increase in tidal volume from 6 to 8 ml/kg would improve the predictability of PVI in patients receiving low tidal volume ventilation in surgical procedures with large fluid shift as hepatobiliary and pancreatic procedures.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Effects of tidal volume challenge on the reliability of plethysmography variability index in hepatobiliary and pancreatic surgeries: a prospective interventional study.
Botros JM, Salem YSM, Khalil M, Algyar MF, et al · · 2023 · cited 2× · PMID 36933167 · DOI 10.1007/s10877-023-00977-8
Verify or expand the search:
- PubMed search for NCT03546179
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
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Trials by the same sponsor.
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Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03546179 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Fayoum University Hospital
- Last refreshed: 7 July 2020
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03546179.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing