Taurolidine Citrate and Unfractionated Heparin Combination Versus Unfractionated Heparin Alone in Prevention of Inflammation in Hemodialysis Catheters.

NCT03539718 Phase 4 UNKNOWN

To assess the efficacy of Taurolock-hep500™ as anticoagulant and antimicrobial catheter lock solution in comparison to unfractionated heparin as alock solution to improve performance of hemodialysis catheters and quality of hemodialysis .

Details

Lead sponsor	Ain Shams University
Phase	Phase 4
Status	UNKNOWN
Enrolment	60
Start date	2018-05-15
Completion	2019-02

Conditions

• Hemodialysis Catheter Infection
• Thrombosis; Dialysis Catheter

Interventions

• Taurolidine heparin
• Heparin Sodium

Primary outcomes

• Prevention of inflammation in hemodialysis patients through hemodialysis catheters — one month
  Comparing levels of highly sensitive c-reactive protein and interleukin-6 levels before and after using the drug Urea reduction ratio over sessions

Countries

Egypt