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Analysis of Cytokine Expression Pattern in Systemic Sclerosis (SCLEROKINE)
By contrast to other proinflammatory cytokines which are found up-regulated in the skin of patients with psoriasis, atopic dermatitis or systemic sclerosis, IL-34 is the only cytokine that undergoes down-regulation. This finding is interesting regarding the description of IL-34 as an immunosuppressive cytokine. In this study, the expression and the role of interleukin-34 (IL-34) will be investigated in the physiopathology of systemic sclerosis.
Details
| Lead sponsor | Poitiers University Hospital |
|---|---|
| Phase | NA |
| Status | COMPLETED |
| Enrolment | 22 |
| Start date | Thu Jul 12 2018 00:00:00 GMT+0000 (Coordinated Universal Time) |
| Completion | Wed Sep 04 2019 00:00:00 GMT+0000 (Coordinated Universal Time) |
Conditions
- Systemic Sclerosis
Interventions
- Skin biopsies
Countries
France