NCT03536624 (ThermStress) is a NA clinical trial of 6 days spa residential program in Stress, sponsored by University Hospital, Clermont-Ferrand.

Who is sponsoring NCT03536624?

NCT03536624 is sponsored by University Hospital, Clermont-Ferrand.

What drugs are being tested in NCT03536624?

Interventions in NCT03536624: 6 days spa residential program.

What condition does NCT03536624 study?

NCT03536624 studies Stress, Burn Out, Heart Rate Variability.

Is NCT03536624 still recruiting?

NCT03536624 is currently status unknown. Last updated 24 May 2018.

Last reviewed 2018-05-24 · How we verify

NCT03536624: ThermStress

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Effects of a Thermal Spa Short Residential Program for Prevention of Work-related Stress / Burn-out on Biomarkers of Stress - A Proof of Concept Study

Status unknown NA Last updated 24 May 2018

What this trial tests

NA trial testing 6 days spa residential program in Stress in 60 participants. Status unknown.

Timeline

1 March 2017

Primary endpoint
1 March 2021

1 March 2021

Quick facts

Lead sponsor	University Hospital, Clermont-Ferrand
Phase	NA
Status	Status unknown
Study type	INTERVENTIONAL
Allocation	na
Design	single group
Masking	none
Primary purpose	prevention
Enrollment	60
Start date	1 March 2017
Primary completion	1 March 2021
Estimated completion	1 March 2021
Sites	1 location across France

Drugs / interventions tested

6 days spa residential program

Conditions studied

Stress — all drugs for Stress →
Burn Out — all drugs for Burn Out →
Heart Rate Variability — all drugs for Heart Rate Variability →

Sponsor

University Hospital, Clermont-Ferrand

Who can join

18 and older, any sex, with Stress or Burn Out. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Work-related stress is a public health issue. Among the multiple physical and psychological consequences of stress, increased mortality and cardiovascular morbidity seem the main concern. The thermal spa resort of Néris-Les-Bains is one of the five spa resorts in France specialized in the treatment of psychosomatic disorders. Among all these resorts proposing a thermal residential program of three weeks, only one thermal spa resort (Saujon) has a program for occupational burn-out. However, a shorter thermal spa residential program seems more compatible with professional context (availability of individuals), and focusing on work-related stress prevention (before the state of burn-out). The main hypothesis is that a short thermal spa residential program (6 days) of work-related stress prevention will exhibit its efficacy through objective measures of well-being and cardiovascular morbidity.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

Effects of a short residential thermal spa program to prevent work-related stress/burnout on stress biomarkers: the ThermStress proof of concept study.
Dutheil F, Chaplais E, Vilmant A, Lanoir D, et al · · 2019 · cited 6× · PMID 31510825 · DOI 10.1177/0300060519859119

Verify or expand the search:

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Currently open trials in the same condition.

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Other University Hospital, Clermont-Ferrand trials

Trials by the same sponsor.

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NCT07427537 — Exploration of Circulating microRNAs as Biomarkers of Chemo-induced Peripheral Neuropathy: a Study in Cancer Patients · NA · recruiting
NCT07330856 — Evaluation of Treatments for Dry or Productive Cough · Phase 4 · not yet recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03536624 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by University Hospital, Clermont-Ferrand
Last refreshed: 24 May 2018

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03536624.

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