Bismuth Subsalicylate's Role in the Prevention of Travelers' Diarrhea

NCT03535272 PHASE3 TERMINATED Results posted

The purpose of this study is to determine if the use of prophylactic bismuth subsalicylate (BSS) has an effect on the acquisition of travelers' diarrhea (TD) or antimicrobial resistance (AMR) genes in fecal samples among international travelers who departed from the United States to South East Asia, South Central Asia, or Africa. Our hypotheses will be tested using a double-blinded, placebo controlled randomized clinical trial with participants from a pre-travel health clinic in the United States.

Details

Lead sponsor	Centers for Disease Control and Prevention
Phase	PHASE3
Status	TERMINATED
Enrolment	482
Start date	Sun May 20 2018 00:00:00 GMT+0000 (Coordinated Universal Time)
Completion	Sun Dec 31 2023 00:00:00 GMT+0000 (Coordinated Universal Time)

Conditions

• Diarrhea Travelers
• Antibiotic Resistant Infection

Interventions

• Bismuth subsalicylate
• Placebo Oral Tablet

Countries

United States