Does the Preoperative Midazolam Dose Affect Postoperative Pain? - a Multicentric Randomized Controlled Trial in Ambulatory Surgery

NCT03534895 Phase 4 UNKNOWN

To investigate whether midazolam has any effect on postoperative pain in outpatient surgery, the investigators will assess the impact of different midazolam doses on pain scores 24h, 7 days and 3 months after ambulatory surgery. The investigators hypothesize that patients being administered higher midazolam doses will refer more pain.

Details

Lead sponsor	Universidade do Porto
Phase	Phase 4
Status	UNKNOWN
Enrolment	168
Start date	2019-05
Completion	2020-08

Conditions

• Pain, Postoperative

Interventions

• Midazolam Injectable Solution
• Normal saline
• Spinal anesthesia
• Surgery
• Postoperative analgesia
• Rescue analgesia
• Wound infiltration
• Analgesia at home

Primary outcomes

• Postoperative pain — Day 1 after surgery
  Assessed by the Brief Pain Inventory severity score (24h recall time): mean of 4 items assessing pain at the moment of the interview, on average, at its least and at its worst during the last 24h

Countries

Portugal