NCT03532113 is a NA clinical trial of Updating in Inhibition (Psychology), sponsored by Centre de Recherche de l'Institut Universitaire de Geriatrie de Montreal.

Who is sponsoring NCT03532113?

NCT03532113 is sponsored by Centre de Recherche de l'Institut Universitaire de Geriatrie de Montreal.

What drugs are being tested in NCT03532113?

Interventions in NCT03532113: Updating, Inhibition, General knowledge.

What condition does NCT03532113 study?

NCT03532113 studies Inhibition (Psychology), Updating, General Knowledge, No Training.

Is NCT03532113 still recruiting?

NCT03532113 is currently completed. Last updated 23 January 2020.

Last reviewed 2020-01-23 · How we verify

NCT03532113

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Attentional Control Training in Older Adults: Efficacy, Transfer and Brain Substrates

Completed NA Last updated 23 January 2020

What this trial tests

NA trial testing Updating in Inhibition (Psychology) in 90 participants. Completed in 20 December 2019.

Timeline

19 October 2017

Primary endpoint
20 December 2019

20 December 2019

Quick facts

Lead sponsor	Centre de Recherche de l'Institut Universitaire de Geriatrie de Montreal
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	supportive care
Enrollment	90
Start date	19 October 2017
Primary completion	20 December 2019
Estimated completion	20 December 2019
Sites	1 location across Canada

Drugs / interventions tested

Updating
Inhibition
General knowledge

Conditions studied

Inhibition (Psychology) — all drugs for Inhibition (Psychology) →
Updating — all drugs for Updating →
General Knowledge — all drugs for General Knowledge →
No Training — all drugs for No Training →

Sponsor

Centre de Recherche de l'Institut Universitaire de Geriatrie de Montreal

Who can join

Adults 60 to 85, any sex, with Inhibition (Psychology) or Updating. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Formal education and cognitively stimulating hobbies and profession have a protective effect against age-related cognitive decline and Alzheimer's disease. It is therefore possible that providing cognitively stimulating interventions at a later age increases neuroplasticity and brain resilience. Processes of updating and inhibition are both impaired by aging. Several studies have shown that updating can be improved but very few studies targeted inhibition in spite of the fact that it is impaired in older adults. The aim of this study is to assess the effect of cognitive interventions that will target either of these two components. The investigators will examine the effect on behavior, brain measures and transfer tasks. The investigators will also assess whether the efficacy varies as a function of personal variables such as prior cognitive profile, reserve proxies, genetic polymorphisms and brain markers.

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

Effects of Computerized Updating and Inhibition Training in Older Adults: The ACTOP Three-Arm Randomized Double-Blind Controlled Trial.
Boujut A, Verty LV, Maltezos S, Lussier M, et al · · 2020 · cited 6× · PMID 33343503 · DOI 10.3389/fneur.2020.606873
Assessing the Effect of Training on the Cognition and Brain of Older Adults: Protocol for a Three-Arm Randomized Double-Blind Controlled Trial (ACTOP).
Boujut A, Mellah S, Lussier M, Maltezos S, et al · · 2020 · cited 3× · PMID 33231556 · DOI 10.2196/20430
Youth-like brain activation linked with greater cognitive training gains in older adults: Insights from the ACTOP study.
Verty LV, Mellah S, Maltezos S, Boujut A, et al · · 2024 · PMID 38805784 · DOI 10.1016/j.cortex.2024.04.013

Verify or expand the search:

Other Centre de Recherche de l'Institut Universitaire de Geriatrie de Montreal trials

Trials by the same sponsor.

NCT06888713 — Telemonitoring of Activities of Daily Living in Home Care Services of Older Adults with Cognitive Deficits · NA · not yet recruiting
NCT07427693 — Usability, Acceptability and Effect of a Mobile Application and Connected Object for Older Women With UI · NA · active not recruiting
NCT06110234 — Efficacy, Transfer, and Neuro-functional Basis of a Memory Training Targeting Episodic Retrieval in Older Adults. · NA · completed
NCT03506672 — Assessing the Effectiveness of an Approach for Vocal Behaviors in Older People Living in Nursing Homes · NA · completed
NCT03400384 — Trial Applying Policy to Eliminate or Reduce Inappropriate Narcotics in the General-population · NA · completed

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03532113 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 9 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Centre de Recherche de l'Institut Universitaire de Geriatrie de Montreal
Last refreshed: 23 January 2020

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03532113.

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