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NCT03530358: MOSE
MOdularity for SEnsory Motor Control
NA trial testing Technology-aided rehabilitation in Stroke, Ischemic in 132 participants. Status unknown.
1 December 2018
Quick facts
| Lead sponsor | IRCCS San Camillo, Venezia, Italy |
|---|---|
| Phase | NA |
| Status | Status unknown |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | double |
| Primary purpose | treatment |
| Enrollment | 132 |
| Start date | 1 December 2014 |
| Primary completion | 1 December 2018 |
| Estimated completion | 1 December 2022 |
| Sites | 2 locations across Italy |
Drugs / interventions tested
- Technology-aided rehabilitation
- Conventional rehabilitation
Conditions studied
- Stroke, Ischemic — all drugs for Stroke, Ischemic →
- Upper Limb Injury — all drugs for Upper Limb Injury →
- Rehabilitation — all drugs for Rehabilitation →
Sponsor
IRCCS San Camillo, Venezia, Italy
Who can join
18 and older, any sex, with Stroke, Ischemic or Upper Limb Injury. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
For this project the investigators ask, how the activation and organization of muscle synergies may be disrupted by brain lesions, and whether it is possible to modify synergy activations by means of specific therapies. Will be investigated whether there is a relationship between post-stroke cortical plasticity and changes in synergy activations due to a therapy.
Publications & conference data
6 peer-reviewed publications reference this trial (live from Europe PMC):
-
Effects of robot therapy on upper body kinematics and arm function in persons post stroke: a pilot randomized controlled trial.
Carpinella I, Lencioni T, Bowman T, Bertoni R, et al · · 2020 · cited 32× · PMID 32000790 · DOI 10.1186/s12984-020-0646-1 -
A randomized controlled trial on the effects induced by robot-assisted and usual-care rehabilitation on upper limb muscle synergies in post-stroke subjects.
Lencioni T, Fornia L, Bowman T, Marzegan A, et al · · 2021 · cited 31× · PMID 33674675 · DOI 10.1038/s41598-021-84536-8 -
Muscle Synergies and Clinical Outcome Measures Describe Different Factors of Upper Limb Motor Function in Stroke Survivors Undergoing Rehabilitation in a Virtual Reality Environment.
Maistrello L, Rimini D, Cheung VCK, Pregnolato G, et al · · 2021 · cited 16× · PMID 34884003 · DOI 10.3390/s21238002 -
Surface-Electromyography-Based Co-Contraction Index for Monitoring Upper Limb Improvements in Post-Stroke Rehabilitation: A Pilot Randomized Controlled Trial Secondary Analysis.
Bandini V, Carpinella I, Marzegan A, Jonsdottir J, et al · · 2023 · cited 12× · PMID 37687775 · DOI 10.3390/s23177320 -
Muscle Synergy Analysis for Clinical Characterization of Upper Limb Motor Recovery After Stroke.
Pregnolato G, Severini G, Maistrello L, Rimini D, et al · · 2026 · cited 3× · PMID 40484193 · DOI 10.1016/j.apmr.2025.05.019 -
Characterization of motor function recovery using muscle synergies in stroke patients undergoing upper limb rehabilitation
Pregnolato G, Severini G, Maistrello L, Rimini D, et al · · 2024 · DOI 10.1101/2024.09.24.24314287
Verify or expand the search:
- PubMed search for NCT03530358
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
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Currently open trials in the same condition.
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- NCT07135089 — Improving Neuroprotective Strategy for Ischemic Stroke Before Endovascular Thrombectomy by Intravenous Tirofiban · Phase 3 · recruiting
- NCT07047014 — Advancing Reperfusion Therapy for Ischemic Stroke (ARTS): Tenecteplase in Medium Vessel Occlusion (MeVO) for Acute Ische · Phase 3 · recruiting
Other IRCCS San Camillo, Venezia, Italy trials
Trials by the same sponsor.
- NCT05956132 — Clinical and Biochemical Features for the Identification of Dominant Calpainopathies · unknown
- NCT05934188 — Exploring the Gut-Brain Axis in Ageing and Neurodegeneration · recruiting
- NCT06264037 — The Experience in Neurorehabilitation Setting: a Qualitative Study · unknown
- NCT06270420 — Technological Devices and Home Automation System in Neurological Rehabilitation · NA · unknown
- NCT05591040 — Biofeedback as an Adjunctive Treatment for Post-stroke Dysphagia · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03530358 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by IRCCS San Camillo, Venezia, Italy
- Last refreshed: 8 June 2022
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03530358.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing