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NCT03526614: RE-SCORE

REpetitive Assessement of SCOREs in Patients on Dual Antiplatelet Therapy

Completed Last updated 19 April 2021
What this trial tests

trial in Dual Anti-platelet Therapy in 480 participants. Completed in 31 December 2019.

Timeline
1 June 2017
Primary endpoint
31 December 2019
31 December 2019

Quick facts

Lead sponsorUniversity of Roma La Sapienza
StatusCompleted
Study typeOBSERVATIONAL
Enrollment480
Start date1 June 2017
Primary completion31 December 2019
Estimated completion31 December 2019
Sites1 location across Italy

Conditions studied

Sponsor

University of Roma La Sapienza

Who can join

18 and older, any sex, with Dual Anti-platelet Therapy. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Patients treated with percutaneous coronary intervention (PCI) require dual antiplatelet therapy (DAPT). Preliminary assessment of the PRECISE-DAPT score is mandatory in order to assess the risk of bleeding while on DAPT. The score takes into consideration age, creatinine clearance, haemoglobin, white-blood-cell count and previous spontaneous bleeding. One should consider, however, that some of the variables included in the PRECISE-DAPT score might change with time. As a consequence, the PRECISE-DAPT score should not be considered a static score as it might vary after the initial computation. It remains unknown, however, if the delta PRECISE-SCORE, reflecting the change in score between baseline and follow-up, might predict more reliably the long-term bleeding risk of PCI patients.

Publications & conference data

1 peer-reviewed publication reference this trial (live from Europe PMC):

  1. Gender-related differences in changes of estimated bleeding risk in patients on dual antiplatelet therapy: the RE-SCORE multicenter prospective registry.
    Pelliccia F, Gragnano F, Pasceri V, Marazzi G, et al · · 2022 · cited 3× · PMID 35875853 · DOI 10.1080/09537104.2022.2102602

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