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NCT03512938

Effects of Smoking on Non-surgical Periodontal Therapy in Generalized Aggressive Periodontitis

Completed NA Last updated 1 May 2018
What this trial tests

NA trial testing Non-surgical periodontal therapy in Generalized Aggressive Periodontitis in 27 participants. Completed in 28 September 2017.

Timeline
23 June 2014
Primary endpoint
8 February 2016
28 September 2017

Quick facts

Lead sponsorEge University
PhaseNA
StatusCompleted
Study typeINTERVENTIONAL
Allocationnon randomized
Designparallel
Maskingnone
Primary purposetreatment
Enrollment27
Start date23 June 2014
Primary completion8 February 2016
Estimated completion28 September 2017

Drugs / interventions tested

Conditions studied

Sponsor

Ege University

Who can join

Adults 18 to 40, any sex, with Generalized Aggressive Periodontitis or Smoking. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

Smoking is the major preventable risk factor in the initiation and progression of periodontal diseases. Periodontitis risk was found to be 3.9 times higher among smokers aged between 19-30 years and 2.8 times higher among smokers aged 31-40 years compared to non-smokers. Aggressive periodontitis (AgP), is characterized by a rapid attachment loss usually incompatible with the amount of plaque and dental calculus. It is often not possible to predict the prognosis of treatment with various treatment options in cases of aggressive periodontitis. It was hypothesized that non-smoker patients with generalized aggressive periodontitis (GAgP) will respond better to conventional mechanical non-surgical periodontal therapy compared to the smokers. Therefore, the aim of this study was to evaluate the effects of smoking on the outcomes of non-surgical periodontal treatment in terms of the clinical, biochemical and microbiological parameters.

Publications & conference data

No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.

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Other trials of Non-surgical periodontal therapy

Trials testing the same drug.

Other Ege University trials

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