NCT03511092 (LMET2IMPROVE) is a NA clinical trial of HMB-FA in Resistance Training, sponsored by Faculdade de Motricidade Humana.

Who is sponsoring NCT03511092?

NCT03511092 is sponsored by Faculdade de Motricidade Humana.

What drugs are being tested in NCT03511092?

Interventions in NCT03511092: HMB-FA, HMB-Ca, alfa-HICA, Placebo comparator.

What condition does NCT03511092 study?

NCT03511092 studies Resistance Training.

Is NCT03511092 still recruiting?

NCT03511092 is currently completed. Last updated 22 February 2024.

Last reviewed 2024-02-22 · How we verify

NCT03511092: LMET2IMPROVE

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

The Effects of Leucine Metabolites in Performance, Body Composition and Biochemical Markers of Muscle Damage

Completed NA Last updated 22 February 2024

What this trial tests

NA trial testing HMB-FA in Resistance Training in 53 participants. Completed in 28 October 2017.

Timeline

29 May 2017

Primary endpoint
28 October 2017

28 October 2017

Quick facts

Lead sponsor	Faculdade de Motricidade Humana
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	randomized
Design	parallel
Masking	double
Primary purpose	basic science
Enrollment	53
Start date	29 May 2017
Primary completion	28 October 2017
Estimated completion	28 October 2017
Sites	1 location across Portugal

Drugs / interventions tested

HMB-FA
HMB-Ca
alfa-HICA
Placebo comparator

Conditions studied

Resistance Training — all drugs for Resistance Training →

Sponsor

Faculdade de Motricidade Humana

Who can join

Adults 18 to 45, male only, with Resistance Training. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

This study aimed to conduct a double-blind randomized pragmatic trial to evaluate the effects of off-the-shelf leucine metabolite supplements HMB-FA, HMB-Ca, alfa-HICA, on resistance training-induced changes in body composition, performance and biochemical markers of muscle damage. The investigators' working hypothesis is that so long as subjects adhered to a diet containing adequate energy and dietary protein, there would be no differences between those receiving the leucine metabolites - HMB-FA, HMB-Ca and alfa-HICA - when compared to a placebo consuming group.

Publications & conference data

2 peer-reviewed publications reference this trial (live from Europe PMC):

Leucine metabolites do not induce changes in phase angle, bioimpedance vector analysis patterns, and strength in resistance trained men.
Campa F, Matias CN, Teixeira FJ, Reis JF, et al · · 2021 · cited 10× · PMID 33337947 · DOI 10.1139/apnm-2020-0915
Association between Phase Angle from Bioelectric Impedance and Muscular Strength and Power in Physically Active Adults.
Fukuoka AH, de Oliveira NM, Matias CN, Teixeira FJ, et al · · 2022 · cited 7× · PMID 36138734 · DOI 10.3390/biology11091255

Verify or expand the search:

Other recruiting trials for Resistance Training

Currently open trials in the same condition.

NCT06360536 — Remotely Delivered Resistance Training for Cardiometabolic Health Among Black Women · NA · recruiting
NCT06765486 — Exercise-Induced Hypoalgesia Differences Between Upper and Lower Limbs Resistance Training Interventions · NA · recruiting
NCT06679491 — Impact of Menstrual Cycle-Based Resistance Training on Neuromuscular Performance in Female Athletes · NA · recruiting
NCT07347912 — Group-based Resistance Training for Adults With Down Syndrome · NA · active not recruiting
NCT06536803 — Effects of High Load Strength Training With and Without Tissue Specific Planter Facia Stretching With Planter Fasciitis · NA · recruiting

Other Faculdade de Motricidade Humana trials

Trials by the same sponsor.

NCT07079722 — More Health Less Diabetes · NA · recruiting
NCT06919237 — Effects of Heart Rate Variability-guided Training vs Standard Aerobic Prescription on Cardiovagal Modulation and Cardior · NA · not yet recruiting
NCT05090501 — The Effects of High Intensity Circuit Training in Nature Vs. Indoor on Exercise Performance, and Wellbeing · NA · completed
NCT07105410 — Hypoalgesic Effects of Exercise and Training of Different Modalities · NA · completed
NCT05380089 — Effects of Hydration Changes on Neuromuscular Function of Athletes · NA · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03511092 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Faculdade de Motricidade Humana
Last refreshed: 22 February 2024

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03511092.

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