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NCT03510962: SALPH-F
Comparison of 5 Buffering Agents on Changes in Salivary pH in Individuals Previously Exposed to a Test Fruit Juice
NA trial testing Group 1: no intervention in Saliva Altered in 30 participants. Completed in 5 December 2018.
5 July 2018
Quick facts
| Lead sponsor | Dr Meru S |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | crossover |
| Masking | single |
| Primary purpose | prevention |
| Enrollment | 30 |
| Start date | 25 April 2018 |
| Primary completion | 5 July 2018 |
| Estimated completion | 5 December 2018 |
| Sites | 1 location across India |
Drugs / interventions tested
- Group 1: no intervention
- Group 2: tap water gargle
- Group 3: 0.2% Chlorhexidine — full drug profile →
- Group 4: Fluoridated tooth paste
- Group 5: Polyol containing gum
- Group 6: 1% sodium bicarbonate solution
Conditions studied
- Saliva Altered — all drugs for Saliva Altered →
- Oral Hygiene — all drugs for Oral Hygiene →
- pH — all drugs for pH →
- Tooth Structure; Disorder — all drugs for Tooth Structure; Disorder →
Sponsor
Dr Meru S — full company profile →
Who can join
Adults 18 to 30, any sex, with Saliva Altered or Oral Hygiene. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
The diurnal variation in the flow of saliva and hence the composition of saliva is an established fact. Consumption of most types of acidic and sweetened foods and beverages are known to reduce the pH of saliva and some of them even reduce it to critical pH levels and result in structural damage to the hard tissues of the tooth. The purpose of this study is to ascertain the effect of the selected commercially available test fruit-juice drink on the salivary pH and assess the buffering capacity of the saliva with or without various intervention measures following the exposure to the test fruit-juice drink at different time intervals.
Publications & conference data
No peer-reviewed publications indexed yet for this trial. Completed trials usually publish results within 12-18 months.
Verify or expand the search:
- PubMed search for NCT03510962
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Group 1: no intervention
Trials testing the same drug.
- NCT03526770 — Comparison of 5 Buffering Agents on Changes in Salivary pH in Individuals Previously Exposed to a Test Carbonated Drink · NA · completed
- NCT03513575 — Comparison of 5 Buffering Agents on Changes in Salivary pH in Individuals Previously Exposed to a Test Flavoured Milk · NA · completed
Other Dr Meru S trials
Trials by the same sponsor.
- NCT03526770 — Comparison of 5 Buffering Agents on Changes in Salivary pH in Individuals Previously Exposed to a Test Carbonated Drink · NA · completed
- NCT03513575 — Comparison of 5 Buffering Agents on Changes in Salivary pH in Individuals Previously Exposed to a Test Flavoured Milk · NA · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03510962 (US National Library of Medicine, public domain)
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Dr Meru S
- Last refreshed: 6 December 2018
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03510962.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing