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NCT03497884
Individualized Precise Localization of rTMS on Primary Motor Area
NA trial testing rTMS in Parkinson Disease in 38 participants. Completed in 15 April 2018.
15 April 2018
Quick facts
| Lead sponsor | Hangzhou Normal University |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | parallel |
| Masking | single |
| Primary purpose | treatment |
| Enrollment | 38 |
| Start date | 4 September 2017 |
| Primary completion | 15 April 2018 |
| Estimated completion | 15 April 2018 |
| Sites | 2 locations across China |
Drugs / interventions tested
- rTMS
Conditions studied
- Parkinson Disease — all drugs for Parkinson Disease →
Sponsor
Hangzhou Normal University
Who can join
Adults 19 to 30, any sex, with Parkinson Disease. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
Parkinson's disease (PD) patients have some problem with self-initiated movement task. Compared with health controls, task meta-analysis found that PD patients showed abnormal activation in pre-supplementary motor area (pre-SMA) and putamen. And the functional connectivity has already been reported between pre-SMA and putamen in 2013. Repetitive Transcranial Magnetic Stimulation (rTMS) is a sage and painless technique to activate cortical areas. The deep brain structure can be activated via stimulating superficial cortex by rTMS. For investigating the mechanism of self-initiated movement, this project is using functional magnetic resonance imaging (fMRI) to individualize the precise localization in motor area and combining rTMS to activate putamen.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Low-frequency rTMS targeting individual self-initiated finger-tapping task activation modulates the amplitude of local neural activity in the putamen.
Wang J, Deng XP, Hu YS, Yue J, et al · · 2023 · cited 7× · PMID 36562546 · DOI 10.1002/hbm.26045
Verify or expand the search:
- PubMed search for NCT03497884
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of rTMS
Trials testing the same drug.
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- NCT07580989 — Network Effects of Left M1 rTMS: A TMS-EEG Study · NA · recruiting
- NCT07567053 — Repetitive Transcranial Magnetic Stimulation on Motor Function and Meta-Plasticity in Cerebral Palsy: TMS-EEG Study · NA · not yet recruiting
- NCT07451600 — Effectiveness of TMS on Spasticity and Balance for Patients With MS · NA · recruiting
- NCT04532190 — Finding Alternatives to Standard Treatment for Attention-Deficit Hyperactivity Disorder · NA · recruiting
Other recruiting trials for Parkinson Disease
Currently open trials in the same condition.
- NCT07399496 — Accelerated TMS for Apathy in PD · NA · recruiting
- NCT07371338 — Phase 1 Clinical Trial to Evaluate the Safety, Efficacy, and Pharmacokinetics of IPS101A in Parkinson's Disease Patients · Phase 1 · recruiting
- NCT07442370 — The Effect of Functional Rotational Exercises on Fall Risk and Mobility in Parkinson's Disease Patients · NA · recruiting
- NCT06848205 — Percept Transitions in FOG and PD · NA · recruiting
- NCT07432958 — A Study to Evaluate the Effectiveness of Two Doses of AP-472 as Adjunctive Therapy to Levodopa in Parkinson's Disease (P · Phase 2 · recruiting
Other Hangzhou Normal University trials
Trials by the same sponsor.
- NCT06536985 — Effect of an Oral Frailty Measures Intervention Programs in Institutionalized Elders · NA · not yet recruiting
- NCT06519695 — Exercise Intervention for Pre-frail Elderly · NA · active not recruiting
- NCT05496985 — Chinese Validation of the Simplified Evaluation of CONsciousness Disorders(SECONDs) · NA · completed
- NCT06014476 — Psychological Symptoms and Burden in Caregivers of Patients With Disorders of Consciousness · completed
- NCT06770348 — Investigating the Localization of Consciousness Through Patients with Disorders of Consciousness: Anterior Vs. Posterior · completed
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03497884 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Hangzhou Normal University
- Last refreshed: 30 May 2018
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03497884.
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