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NCT03497260: FruDeg
Fructose in Exercising Individuals With Type 1 Diabetes Using Insulin Degludec
NA trial testing Fructose in Type 1 Diabetes Mellitus in 15 participants. Completed in 8 September 2019.
6 September 2019
Quick facts
| Lead sponsor | Insel Gruppe AG, University Hospital Bern |
|---|---|
| Phase | NA |
| Status | Completed |
| Study type | INTERVENTIONAL |
| Allocation | randomized |
| Design | crossover |
| Masking | none |
| Primary purpose | supportive care |
| Enrollment | 15 |
| Start date | 4 January 2019 |
| Primary completion | 6 September 2019 |
| Estimated completion | 8 September 2019 |
| Sites | 1 location across Switzerland |
Drugs / interventions tested
- Fructose (FRUCTOSE) — full drug profile →
- Plain water
Conditions studied
- Type 1 Diabetes Mellitus — all drugs for Type 1 Diabetes Mellitus →
- Diabetes Complications — all drugs for Diabetes Complications →
Sponsor
Insel Gruppe AG, University Hospital Bern
Who can join
Adults 18 to 45, male only, with Type 1 Diabetes Mellitus or Diabetes Complications. Patients with the condition only — healthy volunteers not accepted.
Sponsor's own description
To determine and compare the time-to-hypoglycaemia (defined as plasma glucose \<3.9mmol/L) in individuals with type 1 diabetes treated with ultra-Long acting insulin degludec during aerobic exercise with or without prior ingestion of a single oral fructose load.
Publications & conference data
1 peer-reviewed publication reference this trial (live from Europe PMC):
-
Effects of Aerobic Exercise on Systemic Insulin Degludec Concentrations in People with Type 1 Diabetes.
Herzig D, Groessl M, Álvarez-Martínez M, Reverter-Branchat G, et al · · 2023 · cited 3× · PMID 34590906 · DOI 10.1177/19322968211043915
Verify or expand the search:
- PubMed search for NCT03497260
- Europe PMC full search
- ASCO Meeting Library
- ESMO Meeting Library
- bioRxiv preprints
- medRxiv preprints
- Google Scholar
Related trials
Other trials of Fructose
Trials testing the same drug.
- NCT06329544 — High Fructose Diet, the Gut Microbiome, and Metabolic Health · NA · recruiting
- NCT03939130 — Fructose Rich Diet and Endothelial Function · NA · completed
- NCT03067428 — Effects of Fructose Restriction on Liver Steatosis · NA · completed
- NCT03247114 — fMRI of Hypothalamic Responses to Glucose, Fructose, Sucrose and Sucralose · NA · completed
- NCT03157960 — Effect of Acute Fructose Load in Human · NA · completed
Other recruiting trials for Type 1 Diabetes Mellitus
Currently open trials in the same condition.
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- NCT07296276 — Accuracy and Precision of the Continuous Glucose Monitoring System 'CareSens Air 3' in Adult Patients With T1DM · NA · recruiting
- NCT07409701 — Gamification Intervertion in Children With Type 1 Diabetes · NA · recruiting
- NCT07356089 — Twiist Postmarket Surveillance Study for Type 1 Diabetes · recruiting
- NCT07434154 — Evaluation of Oxidative Stress: Comparison Between Type 1 Diabetes Mellitus and Latent Autoimmune Diabetes in Adults · recruiting
Other Insel Gruppe AG, University Hospital Bern trials
Trials by the same sponsor.
- NCT06546384 — GLP-1 RA on Alcohol Consumption, Metabolism and Liver Parameters in Patients With Obesity and Fatty Liver Disease · NA · not yet recruiting
- NCT07524049 — Giving Children a Voice in Paediatric Anaesthesia · not yet recruiting
- NCT07415668 — Motor Eloquent Navigated Transcranial Magnetic Stimulation for Radiosurgery Planning · NA · not yet recruiting
- NCT07478536 — Stockholm3 Test Validation in Men on Active Surveillance in Switzerland (CHAS3 Trial) · not yet recruiting
- NCT07201506 — Real-Time Intracardiac Echocardiography for Ventricular Arrhythmia Ablation · NA · recruiting
Verify against primary sources
- ClinicalTrials.gov — authoritative US registry record
- WHO ICTRP — international registry index
- EU Clinical Trials Register
- Sponsor press releases (Google)
- Trial protocol + status: ClinicalTrials.gov NCT03497260 (US National Library of Medicine, public domain)
- Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
- Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
- Sponsor: as reported to ClinicalTrials.gov by Insel Gruppe AG, University Hospital Bern
- Last refreshed: 20 September 2019
Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03497260.
Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing