NCT03494491 is a NA clinical trial of Chitin-glucan in Healthy, sponsored by Université Catholique de Louvain.

Who is sponsoring NCT03494491?

NCT03494491 is sponsored by Université Catholique de Louvain.

What drugs are being tested in NCT03494491?

Interventions in NCT03494491: Chitin-glucan, Maltodextrin.

Is NCT03494491 still recruiting?

NCT03494491 is currently completed. Last updated 11 April 2018.

Last reviewed 2018-04-11 · How we verify

NCT03494491

Name: Drug Landscape Pharmaceutical Database
Creator: Drug Landscape
Published: 2026-01-01
License: https://creativecommons.org/licenses/by/4.0/

Characterization of Chitin-glucan Fiber Fermentation in Human After a Single Administration

Completed NA Last updated 11 April 2018

What this trial tests

NA trial testing Chitin-glucan in Healthy in 15 participants. Completed in 30 March 2018.

Timeline

8 March 2018

Primary endpoint
30 March 2018

30 March 2018

Quick facts

Lead sponsor	Université Catholique de Louvain
Phase	NA
Status	Completed
Study type	INTERVENTIONAL
Allocation	non randomized
Design	crossover
Masking	single
Primary purpose	other
Enrollment	15
Start date	8 March 2018
Primary completion	30 March 2018
Estimated completion	30 March 2018
Sites	1 location across Belgium

Drugs / interventions tested

Chitin-glucan
Maltodextrin (MALTODEXTRIN) — full drug profile →

Conditions studied

Healthy — all drugs for Healthy →

Sponsor

Université Catholique de Louvain — full company profile →

Who can join

Adults 18 to 40, any sex, with Healthy. Patients with the condition only — healthy volunteers not accepted.

Sponsor's own description

The aim of this research study is to characterize the fermentation of chitin-glucan fiber by assessing the volatile compounds released in the breath. For this purpose, an interventional study with control will be performed. After a single administration of 4.5 g of chitin-glucan fiber, the kinetic of production of exhaled volatile compounds (such as H2, methane, SCFAs,…) will be measured during twelve hours. These results will be compared to the exhaled volatile compounds measured during twelve hours after supplementation with 4.5g of maltodextrin (placebo).

Publications & conference data

3 peer-reviewed publications reference this trial (live from Europe PMC):

β-Glucan Metabolic and Immunomodulatory Properties and Potential for Clinical Application.
Murphy EJ, Rezoagli E, Major I, Rowan NJ, et al · · 2020 · cited 121× · PMID 33322069 · DOI 10.3390/jof6040356
Development of a Repertoire and a Food Frequency Questionnaire for Estimating Dietary Fiber Intake Considering Prebiotics: Input from the FiberTAG Project.
Neyrinck AM, Nazare JA, Rodriguez J, Jottard R, et al · · 2020 · cited 16× · PMID 32942686 · DOI 10.3390/nu12092824
Noninvasive monitoring of fibre fermentation in healthy volunteers by analyzing breath volatile metabolites: lessons from the FiberTAG intervention study.
Neyrinck AM, Rodriguez J, Zhang Z, Seethaler B, et al · · 2021 · cited 13× · PMID 33461385 · DOI 10.1080/19490976.2020.1862028

Verify or expand the search:

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Other Université Catholique de Louvain trials

Trials by the same sponsor.

NCT07453524 — Assessing Chronic Pain Patient Preferences · NA · not yet recruiting
NCT07422909 — Bridging the Gap: Implementing BRIDGES · NA · not yet recruiting
NCT07420231 — Evaluation of the Synergistic Effect of Combining a Prebiotic and a Postbiotic on Intestinal Discomfort · NA · not yet recruiting
NCT07360223 — Internalized Symptoms in Adolescents With Autism Spectrum Disorder (ASD) and Typically Developing Adolescents : Gaining · not yet recruiting
NCT07263971 — Birth Experience of Women Giving Birth in Belgium · recruiting

Verify against primary sources

ClinicalTrials.gov — authoritative US registry record
WHO ICTRP — international registry index
EU Clinical Trials Register
Sponsor press releases (Google)

Data sources for this page

Trial protocol + status: ClinicalTrials.gov NCT03494491 (US National Library of Medicine, public domain)
Publications: Europe PMC API search by NCT ID, retrieved 10 June 2026
Drug + disease cross-links: matched in real time against Drug Landscape's normalised drug + company + condition tables
Sponsor: as reported to ClinicalTrials.gov by Université Catholique de Louvain
Last refreshed: 11 April 2018

Drug Landscape aggregates and links these public records for informational use only. Always verify against the primary source before clinical or regulatory decisions. Canonical URL: https://druglandscape.com/trial/NCT03494491.

Primary sources · FDA · ClinicalTrials.gov · EMA · SEC EDGAR · ChEMBL · Wikidata · full sourcing